Reinstating plasticity and memory in a tauopathy mouse model with an acetyltransferase activator
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DOI: 10.15252/emmm.201708587
Abstract: Chromatin acetylation, a critical regulator of synaptic plasticity and memory processes, is thought to be altered in neurodegenerative diseases. Here, we demonstrate that spatial memory and plasticity (LTD, dendritic spine formation) deficits can be restored… read more here.
Keywords: activator; csp ttk21; plasticity memory; mouse model ... See more keywords