Csp3–N bond formation in aminothiophenes by 1,1-dibromo isocyanide: the unexpected 1,5-binucleophilicity of substrates
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-017-1195-9
Abstract: The N-cyclohexylcarbonimidoyl dibromide in situ, generated by cyclohexylisocyanide and bromine in reaction with several deactivated 5-acetyl-4-amino-2-methylsulfanyl-3-carbonitrile, appears as a cyclohexyl transformer to the substrate via Csp3–N bond formation without using any base or catalyst at… read more here.
Keywords: formation aminothiophenes; bond formation; reaction; csp3 bond ... See more keywords
Cu-Catalyzed Aerobic Oxidative Sulfuration/Annulation Approach to Thiazoles via Multiple Csp3-H Bond Cleavage.
Sign Up to like & getrecommendations! Published in 2018 at "Organic letters"
DOI: 10.1021/acs.orglett.8b00840
Abstract: A novel and practical Cu-catalyzed aerobic oxidative synthesis of thiazoles was developed. This chemistry for the first time achieved thiazole construction from simple aldehydes, amines, and element sulfur through multiple Csp3-H bond cleavage processes. Molecular… read more here.
Keywords: sulfuration annulation; multiple csp3; bond cleavage; csp3 bond ... See more keywords
Reusable ionic liquid-catalyzed oxidative esterification of carboxylic acids with benzylic hydrocarbons via benzylic Csp3–H bond activation under metal-free conditions
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DOI: 10.1039/c7ra02788e
Abstract: A metal-free protocol for the direct oxidative esterification of the Csp3–H bond in benzylic hydrocarbons with carboxylic acids using heterocyclic ionic liquid as catalyst has been reported. The catalyst 1-butylpyridinium iodide could be easily recycled… read more here.
Keywords: ionic liquid; benzylic hydrocarbons; carboxylic acids; csp3 bond ... See more keywords
Rh(iii)-catalyzed regioselective intermolecular N-methylene Csp3–H bond carbenoid insertion† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03802j
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c7sc03802j
Abstract: A Rh(iii)-catalyzed regioselective intermolecular carbenoid insertion into the N-methylene Csp3–H bond has been achieved via an outer-sphere pathway. read more here.
Keywords: methylene csp3; regioselective intermolecular; iii catalyzed; csp3 bond ... See more keywords
Rh(iii)-Catalyzed Csp2–Csp3 bond alkoxylation of α-indolyl alcohols via C–C σ bond cleavage
Sign Up to like & getrecommendations! Published in 2021 at "Organic chemistry frontiers"
DOI: 10.1039/d1qo00194a
Abstract: A Rh(iii)-catalyzed direct Csp2–Csp3 bond alkoxylation of α-(2-indolyl)alcohols with alcohols has been achieved via C–C sigma bond/C–O single bond switch. read more here.
Keywords: bond alkoxylation; csp3 bond; alkoxylation indolyl; iii catalyzed ... See more keywords
Chemodivergent Csp3─F bond functionalization and cross-electrophile alkyl-alkyl coupling with alkyl fluorides
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn7819
Abstract: The widespread use of fluorinated organic compounds in the health, agrochemical, and materials sciences is sustained by a steadily growing pool of commercially available fine chemicals. The synthetic utility of the increasingly ubiquitous Csp3─F bond,… read more here.
Keywords: bond; alkyl fluorides; fluorides chemodivergent; cross ... See more keywords