Variability of voriconazole concentrations in patients with hematopoietic stem cell transplantation and hematological malignancies: influence of loading dose, procalcitonin, and pregnane X receptor polymorphisms
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DOI: 10.1007/s00228-020-02831-1
Abstract: Aims Voriconazole (VCZ) displays highly variable pharmacokinetics affecting treatment efficacy and safety. We aimed to identify the factors affecting VCZ steady-state trough concentration (Cssmin) to provide evidence for optimizing VCZ treatment regimens. Methods A total… read more here.
Keywords: cssmin; hematopoietic stem; pxr; vcz ... See more keywords