Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer
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DOI: 10.1002/1878-0261.13796
Abstract: Pancreatic ductal adenocarcinoma (PDAC) is a disease with poor prognosis due to diagnostic and therapeutic limitations. We previously identified cystatin A (CSTA) as a PDAC biomarker and have conducted the present study to investigate the… read more here.
Keywords: csta; antitumor; murine models; dendritic cells ... See more keywords
Cystatin A suppresses tumor cell growth through inhibiting epithelial to mesenchymal transition in human lung cancer
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DOI: 10.18632/oncotarget.23505
Abstract: Cystatin A (CSTA), belonging to type 1 cystatin super-family, is expressed primarily in epithelial and lymphoid tissues for protecting cells from proteolysis of cytoplasmic and cytoskeletal proteins by cathepsins B, H and L. CSTA acts… read more here.
Keywords: lung; lung cancer; cell; csta ... See more keywords
Function and Regulation of the Pyruvate Transporter CstA in Escherichia coli †
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DOI: 10.3390/ijms21239068
Abstract: Pyruvate is a central metabolite that connects many metabolic pathways in living organisms. To meet the cellular pyruvate requirements, the enterobacterium Escherichia coli has at least three pyruvate uptake systems—the H+/pyruvate symporter BtsT, and two… read more here.
Keywords: escherichia coli; csta; pyruvate transporter; pyruvate ... See more keywords