Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1069122
Abstract: Cystatin B (CSTB) is a cysteine cathepsin inhibitor whose biallelic loss-of-function mutations in human result in defects in brain development and in neurodegeneration. The physiological function of CSTB is largely unknown, and the mechanisms underlying… read more here.
Keywords: cathepsin; chromatin associated; brain; postnatal mouse ... See more keywords
Expression and Regulation of a Novel Decidual Cells-Derived Estrogen Target during Decidualization
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DOI: 10.3390/ijms24010302
Abstract: During decidualization in rodents, uterine stromal cells undergo extensive reprogramming to differentiate into distinct cell types, forming primary decidual zones (PDZs), secondary decidual zones (SDZs), and layers of undifferentiated stromal cells. The formation of secondary… read more here.
Keywords: estrogen target; expression; decidualization; cstb ... See more keywords