CSTF2-Induced Shortening of the RAC1 3'UTR Promotes the Pathogenesis of Urothelial Carcinoma of the Bladder.
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DOI: 10.1158/0008-5472.can-18-0822
Abstract: Shortening of the 3' untranslated regions (3'UTR) of mRNA is an important mechanism for oncogene activation. However, 3'UTR alteration events, their pathologic functions, and underlying mechanisms in human urothelial carcinoma of the bladder (UCB) are… read more here.
Keywords: cstf2; cstf2 induced; isoform; urothelial carcinoma ... See more keywords
CSTF2 Promotes Hepatocarcinogenesis and Hepatocellular Carcinoma Progression via Aerobic Glycolysis
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DOI: 10.3389/fonc.2022.897804
Abstract: Background The shortening of 3’ untranslated regions (3’UTRs) of messenger RNAs(mRNAs) by alternative polyadenylation (APA) is an important mechanism for oncogene activation. Cleavage stimulation factor 2 (CSTF2), an important regulator of APA, has been reported… read more here.
Keywords: cstf2 knockout; function; hcc; cstf2 ... See more keywords