Gut microbial alteration in chronic spontaneous urticaria unresponsive to second generation antihistamines and its correlation with disease characteristics‐ a cross‐sectional case‐control study
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DOI: 10.1002/clt2.70027
Abstract: Abstract Background Gut microbial involvement has been speculated in chronic spontaneous urticaria (CSU). The aim of the study was to compare the gut microbiome composition and diversity in CSU patients uncontrolled with second‐generation antihistamines (sgAHs)… read more here.
Keywords: disease; control; study; gut microbial ... See more keywords
Autoimmune comorbidity in chronic spontaneous urticaria: A systematic review.
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DOI: 10.1016/j.autrev.2017.10.003
Abstract: BACKGROUND AND OBJECTIVE Numerous autoimmune diseases (AIDs) have been linked to chronic spontaneous urticaria (CSU). Here, we provide the first extensive and comprehensive evaluation of the prevalence of AIDs in patients with CSU and vice… read more here.
Keywords: spontaneous urticaria; prevalence; chronic spontaneous; csu ... See more keywords
C‐reactive protein (CRP) rs3093059C predicts poor mizolastine response in chronic spontaneous urticaria patients with elevated serum CRP level
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DOI: 10.1111/exd.13874
Abstract: Chronic spontaneous urticaria (CSU) is a frequent disorder with recurrent itchy wheals and/or angioedema, and nearly 35% patients respond poorly to non‐sedating H1 antihistamine treatment. CRP gene encodes the C‐reactive protein, which is involved in… read more here.
Keywords: spontaneous urticaria; reactive protein; csu patients; chronic spontaneous ... See more keywords
Serum Human β-Defensin 2 Is Increased in Angioedema Accompanying Chronic Spontaneous Urticaria.
Sign Up to like & getrecommendations! Published in 2021 at "International archives of allergy and immunology"
DOI: 10.1159/000516952
Abstract: INTRODUCTION Chronic spontaneous urticaria (CSU) is a common cutaneous disease caused by mast-cell degranulation. Human β-defensin 2 (HBD2) is a well-known antimicrobial peptide that is also a pruritogen inducing vascular permeability via non-IgE-mediated mast-cell degranulation.… read more here.
Keywords: spontaneous urticaria; chronic spontaneous; csu; human defensin ... See more keywords
Detection of serum IgG autoantibodies to FcεRIα by ELISA in patients with chronic spontaneous urticaria
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DOI: 10.1371/journal.pone.0273415
Abstract: Background Mast cells are a key effector cell in the pathogenesis of chronic spontaneous urticaria (CSU) and activated by circulating FcεRI-specific IgG as well as IgE. This study evaluated the prevalence of circulating autoantibodies to… read more here.
Keywords: csu patients; spontaneous urticaria; serum; iga igm ... See more keywords
Efficacy of omalizumab for extracutaneous symptoms of chronic spontaneous urticaria
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DOI: 10.1684/ejd.2020.3717
Abstract: The anti-IgE antibody, omalizumab, is an effective treatment for cutaneous symptoms of chronic spontaneous urticaria (CSU) [1]. As some CSU patients exhibit extracutaneous symptoms (CSU+) [2], we studied the evolution of extracutaneous symptoms in CSU+… read more here.
Keywords: years range; spontaneous urticaria; chronic spontaneous; extracutaneous symptoms ... See more keywords
Altered Gut Microbiota in H1-Antihistamine-Resistant Chronic Spontaneous Urticaria Associates With Systemic Inflammation
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DOI: 10.3389/fcimb.2022.831489
Abstract: Background and Objective Chronic spontaneous urticaria (CSU) is a histamine-mediated inflammatory skin disease, and second-generation non-sedating H1-antihistamines (nsAH) at licensed doses have long been the first-line therapy in CSU. However, about 50% of patients are… read more here.
Keywords: csu patients; inflammation; nsah resistance; chronic spontaneous ... See more keywords
The Alarmin Triad—IL-25, IL-33, and TSLP—Serum Levels and Their Clinical Implications in Chronic Spontaneous Urticaria
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DOI: 10.3390/ijms25042026
Abstract: This study delves into the critical role of alarmins in chronic spontaneous urticaria (CSU), focusing on their impact on disease severity and the quality of life (QoL) of patients. We investigated the alterations in alarmin… read more here.
Keywords: severity; spontaneous urticaria; chronic spontaneous; levels clinical ... See more keywords