Articles with "ct26" as a keyword



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Anti‐inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor‐bearing mice

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Published in 2020 at "Journal of Leukocyte Biology"

DOI: 10.1002/jlb.3ma0120-578r

Abstract: Methionine enkephalin (MENK), an endogenous opioid peptide, has a role in nervous system, immune system, and anticancer therapy. Inflammation, metabolism and cancer are closely intertwined with each other. This study is to identify the correlation… read more here.

Keywords: response; mice; ct26 tumor; tumor ... See more keywords

Chromium-based metal-organic framework embedded with cobalt phthalocyanine for the sensitively impedimetric cytosensing of colorectal cancer (CT26) cells and cell imaging

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Published in 2020 at "Chemical Engineering Journal"

DOI: 10.1016/j.cej.2020.125452

Abstract: Abstract In this study, we have prepared the series of nanohybrids of Cr-based metal-organic framework (Cr-MOF) and cobalt phthalocyanine (CoPc) nanoparticles (denoted as Cr-MOF@CoPc) and investigated them as novel platforms of electrochemical cytosensors for determining… read more here.

Keywords: ct26 cells; metal; mof copc; cancer ... See more keywords
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The effect of CT26 tumor-derived TGF-β on the balance of tumor growth and immunity.

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Published in 2017 at "Immunology letters"

DOI: 10.1016/j.imlet.2017.08.024

Abstract: INTRODUCTION TGF-β is an important target for many cancer therapies under development. In addition to suppressing anti-tumor immunity, it has pleiotropic direct pro- and anti- tumor effects. The actions of increased endogenous TGF-β production remain… read more here.

Keywords: tumor; immunity; tgf; ct26 ... See more keywords
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Abstract 6679: Immunophenotypic and transcriptome analyses of CT26 and 4T1 murine tumor models following anti-CTLA-4 treatment

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Published in 2020 at "Immunology"

DOI: 10.1158/1538-7445.am2020-6679

Abstract: Model selection for evaluation of immuno-oncology agents is often aided by both response to therapy and changes in immune cell subsets following treatment. To identify underlying factors that influence differences in therapeutic response, CT26 colorectal… read more here.

Keywords: anti ctla; treatment; ct26; cell ... See more keywords
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A mechanistic investigation exploring the differential transfection efficiencies between the easy-to-transfect SK-BR3 and difficult-to-transfect CT26 cell lines

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Published in 2017 at "Journal of Nanobiotechnology"

DOI: 10.1186/s12951-017-0271-8

Abstract: BackgroundGold–polyamidoamine (AuPAMAM) has previously been shown to successfully transfect cells with high efficiency. However, we have observed that certain cell types are more amenable to Au–PAMAM transfection than others. Here we utilized two representative cell… read more here.

Keywords: transfection; cell lines; ct26; cell ... See more keywords
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Chidamide plus Tyrosine Kinase Inhibitor Remodel the Tumor Immune Microenvironment and Reduce Tumor Progression When Combined with Immune Checkpoint Inhibitor in Naïve and Anti-PD-1 Resistant CT26-Bearing Mice

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231810677

Abstract: Combined inhibition of vascular endothelial growth factor receptor (VEGFR) and the programmed cell death protein 1 (PD-1) pathways has shown efficacy in multiple cancers; however, the clinical outcomes show limited benefits and the unmet clinical… read more here.

Keywords: ct26; regorafenib; combination; inhibitor ... See more keywords
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Anti-Cancer Effects of α-Cubebenoate Derived from Schisandra chinensis in CT26 Colon Cancer Cells

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Published in 2022 at "Molecules"

DOI: 10.3390/molecules27030737

Abstract: α-Cubebenoate derived from Schisandra chinensis has been reported to possess anti-allergic, anti-obesity, and anti-inflammatory effects and to exhibit anti-septic activity, but its anti-cancer effects have not been investigated. To examine the anti-cancer activity of α-cubebenoate,… read more here.

Keywords: ct26; anti cancer; cubebenoate derived; derived schisandra ... See more keywords
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Modulation of the tumor microenvironment by intratumoral administration of IMO-2125, a novel TLR9 agonist, for cancer immunotherapy.

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Published in 2018 at "International journal of oncology"

DOI: 10.3892/ijo.2018.4456

Abstract: The objective of cancer immunotherapy is to prime the host's immune system to recognize and attack malignant tumor cells. IMO‑2125, a Toll‑like receptor 9 (TLR9) agonist, exhibited potent antitumor effects in the murine syngeneic A20 lymphoma and… read more here.

Keywords: administration; imo 2125; ct26; antitumor ... See more keywords