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   Articles with "ctbp1" as a keyword



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SP1-induced upregulation of lncRNA CTBP1-AS2 accelerates the hepatocellular carcinoma tumorigenesis through targeting CEP55 via sponging miR-195-5p.

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recommendations! Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.09.080

Abstract: As reported in many research, LncRNA CTBP1 divergent transcript (CTBP1-AS2) remarkably affects the progression of several tumors. However, the precise role and function of CTBP1-AS2 in hepatocellular carcinoma (HCC) remained unknown. We found that CTBP1-AS2… read more here.

Keywords: mir 195; hcc; lncrna ctbp1; ctbp1 ... See more keywords
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Abstract 3724: RAI2 controls polycomb-mediated repression of CDKN1A by its interaction with CtBP1

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recommendations! Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-3724

Abstract: RAI2 has initially been identified as a metastasis-associated gene in breast cancer. Recently, we found that increased RAI2 protein in primary tumors predicts early biochemical relapse of prostate cancer patients. On the molecular level, RAI2… read more here.

Keywords: interaction; cdkn1a; rai2; ctbp1 ... See more keywords
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PRDM14-CtBP1/2-PRC2 complex regulates transcriptional repression during transition from primed to naïve pluripotency.

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recommendations! Published in 2020 at "Journal of cell science"

DOI: 10.1242/jcs.240176

Abstract: The pluripotency-associated transcriptional network is regulated by a core circuitry of transcription factors. The PR domain-containing protein, PRDM14, maintains pluripotency by activating and repressing transcription in a target gene-dependent manner. However, the mechanisms underlying dichotomic… read more here.

Keywords: transition primed; primed pluripotency; ctbp1; pluripotency ... See more keywords
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Angiotensin II Inhibits Adipogenic Differentiation and Promotes Mature Adipocyte Browning through the Corepressor CtBP1

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recommendations! Published in 2022 at "Biomedicines"

DOI: 10.3390/biomedicines10123131

Abstract: The mechanisms of angiotensin II (Ang II) on regulating adipogenic differentiation and function remain unknown. In this study, we focus on revealing the role of C-terminal-binding protein 1 (CtBP1) on Ang II-mediated adipogenic differentiation and… read more here.

Keywords: adipogenic differentiation; ang; mature adipocyte; adipocyte browning ... See more keywords
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JAC4 Inhibits EGFR-Driven Lung Adenocarcinoma Growth and Metastasis through CTBP1-Mediated JWA/AMPK/NEDD4L/EGFR Axis

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24108794

Abstract: Lung adenocarcinoma (LUAD) is the most common lung cancer, with high mortality. As a tumor-suppressor gene, JWA plays an important role in blocking pan-tumor progression. JAC4, a small molecular-compound agonist, transcriptionally activates JWA expression both… read more here.

Keywords: jac4; lung; growth metastasis; ctbp1 ... See more keywords