Bring along your friends: Homotypic and heterotypic circulating tumor cell clustering to accelerate metastasis
Sign Up to like & getrecommendations! Published in 2020 at "Biomedical Journal"
DOI: 10.1016/j.bj.2019.11.002
Abstract: Metastasis formation is a hallmark of invasive cancers and it is achieved through the shedding of circulating tumor cells (CTCs) from the primary site into the blood circulation. There, CTCs are found as single cells… read more here.
Keywords: metastasis; homotypic heterotypic; ctc clusters; circulating tumor ... See more keywords
A Collective Route to Head and Neck Cancer Metastasis
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DOI: 10.1038/s41598-017-19117-9
Abstract: Distant metastasis (DM) from head and neck cancers (HNC) portends a poor patient prognosis. Despite its important biological role, little is known about the cells which seed these DM. Circulating tumour cells (CTCs) represent a… read more here.
Keywords: ctc clusters; seed; head neck; metastasis ... See more keywords
Abstract P6-10-23: Presence of circulating tumor cell clusters and elevated platelet counts interactively predict disease progression in advanced-stage breast cancer patients
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs19-p6-10-23
Abstract: Background: Circulating tumor cells (CTCs) and their clusters (CTC-clusters) are promising prognostic markers in breast cancer. Recently studies showed that platelets interact with tumor cells in the circulation and promote metastasis. However, no study has… read more here.
Keywords: ctc clusters; breast cancer; platelet counts; cancer ... See more keywords
Abstract TS2-1: CTC Clusters, Cancer Stemness, and New Treatment Strategies
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DOI: 10.1158/1538-7445.sabcs19-ts2-1
Abstract: Circulating tumor cells (CTCs) seed metastases which eventually kill most of the breast cancer patients; however, CTCs have not been effectively targeted partially due to the unclear cellular and molecular mechanisms. Emerging evidence and our… read more here.
Keywords: ctc clusters; cd44; clusters cancer; cancer ... See more keywords
Sequential Isolation and Characterization of Single CTCs and Large CTC Clusters in Metastatic Colorectal Cancer Patients
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DOI: 10.3390/cancers13246362
Abstract: Simple Summary The presence of cancer cells clusters is a frequent event capable of increasing their aptitude to survive in the bloodstream. Consistently, clusters ranging from 2–50 cancer cells are detected in about 50% of… read more here.
Keywords: cancer; isolation; ctc clusters; ctc ... See more keywords