CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming.
Sign Up to like & getrecommendations! Published in 2022 at "Cell reports"
DOI: 10.1016/j.celrep.2022.110626
Abstract: CTCF mediates chromatin insulation and long-distance enhancer-promoter (EP) interactions; however, little is known about how these regulatory functions are partitioned among target genes in key biological processes. Here, we show that Ctcf expression is progressively… read more here.
Keywords: ctcf; ctcf functions; pluripotency; chromatin remodeler ... See more keywords