CTCF knockout in zebrafish induces alterations in regulatory landscapes and developmental gene expression
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DOI: 10.1038/s41467-021-25604-5
Abstract: Coordinated chromatin interactions between enhancers and promoters are critical for gene regulation. The architectural protein CTCF mediates chromatin looping and is enriched at the boundaries of topologically associating domains (TADs), which are sub-megabase chromatin structures.… read more here.
Keywords: ctcf knockout; gene expression; ctcf; gene ... See more keywords