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Spatial patterns of CTCF sites define the anatomy of TADs and their boundaries

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Published in 2020 at "Genome Biology"

DOI: 10.1186/s13059-020-02108-x

Abstract: Topologically associating domains (TADs) are genomic regions of self-interaction. Additionally, it is known that TAD boundaries are enriched in CTCF binding sites. In turn, CTCF sites are known to be asymmetric, whereby the convergent configuration… read more here.

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