Articles with "ctcs" as a keyword



Dynamic monitoring of PD‐L1 and Ki67 in circulating tumor cells of metastatic non‐small cell lung cancer patients treated with pembrolizumab

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Published in 2022 at "Molecular Oncology"

DOI: 10.1002/1878-0261.13317

Abstract: Programmed cell death protein ligand‐1 (PD‐L1) expression in non‐small cell lung cancer (NSCLC) tumors guides treatment selection. PD‐L1 expression in circulating tumor cells (CTCs) may provide further information. We have explored PD‐L1 and marker of… read more here.

Keywords: cell; non small; ki67; small cell ... See more keywords

Precise Capture and Dynamic Release of Circulating Liver Cancer Cells with Dual‐Histidine‐Based Cell Imprinted Hydrogels

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Published in 2024 at "Advanced Materials"

DOI: 10.1002/adma.202402379

Abstract: Circulating tumor cells (CTCs) detection presents significant advantages in diagnosing liver cancer due to its noninvasiveness, real‐time monitoring, and dynamic tracking. However, the clinical application of CTCs‐based diagnosis is largely limited by the challenges of… read more here.

Keywords: cancer; release; liver cancer; cell ... See more keywords

Charge‐Transfer Complexes: Fundamentals and Advances in Catalysis, Sensing, and Optoelectronic Applications

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Published in 2024 at "Advanced Materials"

DOI: 10.1002/adma.202406083

Abstract: Supramolecular assemblies, formed through electronic charge transfer between two or more entities, represent a rich class of compounds dubbed as charge‐transfer complexes (CTCs). Their distinctive formation pathway, rooted in charge‐transfer processes at the interface of… read more here.

Keywords: complexes fundamentals; transfer complexes; charge transfer; transfer ... See more keywords

The prognostic significance of circulating tumor cells in head and neck and non‐small‐cell lung cancer

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Published in 2018 at "Cancer Medicine"

DOI: 10.1002/cam4.1832

Abstract: Tumor biopsy is the gold standard for the assessment of clinical biomarkers for treatment. However, tumors change dynamically in response to therapy, and there remains a need for a more representative biomarker that can be… read more here.

Keywords: tumor cells; circulating tumor; head neck; cancer ... See more keywords

Longitudinal Analysis of Manually and Automatically Classified Circulating Tumor Biomarkers and their Prediction of Survival in Metastatic Colorectal Cancer.

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Published in 2025 at "Clinical pharmacology and therapeutics"

DOI: 10.1002/cpt.70128

Abstract: Circulating tumor cells (CTCs) and tumor‐derived extracellular vesicles (tdEVs) are promising biomarkers for predicting survival and informing treatment decisions in metastatic colorectal cancer (mCRC); yet their clinical application remains limited. In this study, we analyzed… read more here.

Keywords: colorectal cancer; metastatic colorectal; tumor; circulating tumor ... See more keywords

An integrated enrichment system to facilitate isolation and molecular characterization of single cancer cells from whole blood

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Published in 2018 at "Cytometry Part A"

DOI: 10.1002/cyto.a.23599

Abstract: Circulating tumor cells (CTCs) carry valuable biological information. While enumeration of CTCs in peripheral blood is an FDA‐approved prognostic indicator of survival in metastatic prostate and other cancers, analysis of CTC phenotypic and genomic markers… read more here.

Keywords: system; blood; cancer cells; cancer ... See more keywords

Measurable morphological features of single circulating tumor cells in selected solid tumors—A pilot study

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Published in 2024 at "Cytometry Part A"

DOI: 10.1002/cyto.a.24906

Abstract: Liquid biopsies developed into a range of sensitive technologies aiming to analyze for example, circulating tumor cells (CTCs) in peripheral blood, which significantly deepens understanding of the metastatic process. Nevertheless, examination of CTCs is mostly… read more here.

Keywords: morphological features; tumor cells; circulating tumor; epithelial mesenchymal ... See more keywords

Cytomorphologic visualization of circulating tumor cells in urinary bladder cancer patients using ScreenCell™ technology: Potential as a simple cytology test

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Published in 2023 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.25141

Abstract: Circulating tumor cells (CTC) are a recent technique which is a potentially important prognostic factor in many solid tumors. There are many techniques of detecting CTCs, but they usually implement costly techniques like EpCAM targeted… read more here.

Keywords: circulating tumor; tumor cells; ctcs; cytology ... See more keywords

RhoA‐stimulated intra‐capillary morphology switch facilitates the arrest of individual circulating tumor cells

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Published in 2018 at "International Journal of Cancer"

DOI: 10.1002/ijc.31238

Abstract: Metastasis is the primary cause of death for most cancer patients. Hematogenous arrest of circulating tumor cells (CTCs) is an essential prerequisite for metastases formation. Using transparent transgenic zebrafish (kdrl:eGFP; Casper), together with resonant laser… read more here.

Keywords: arrest individual; tumor cells; intra capillary; circulating tumor ... See more keywords

Utilizing Matrigel Transwell Invasion Assay to Detect and Enumerate Circulating Tumor Cells.

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Published in 2017 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7144-2_23

Abstract: Metastasis is the cause of 90% of human cancer deaths. Circulating tumor cells (CTCs) in the peripheral blood and/or lymphatic vessels are cells shed from primary tumors and considered to be precursors of metastasis. Study… read more here.

Keywords: tumor cells; circulating tumor; detect enumerate; ctcs ... See more keywords

Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures.

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Published in 2017 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-319-55947-6_8

Abstract: Cancer kills by metastasizing beyond the primary site. Early detection, surgical intervention and other treatments have improved the survival rates of patients with cancer, however, once metastasis occurs, responses to conventional therapies become significantly less… read more here.

Keywords: tumor cells; genetic signatures; circulating tumor; cancer ... See more keywords