Dynamic monitoring of PD‐L1 and Ki67 in circulating tumor cells of metastatic non‐small cell lung cancer patients treated with pembrolizumab
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13317
Abstract: Programmed cell death protein ligand‐1 (PD‐L1) expression in non‐small cell lung cancer (NSCLC) tumors guides treatment selection. PD‐L1 expression in circulating tumor cells (CTCs) may provide further information. We have explored PD‐L1 and marker of… read more here.
Keywords: cell; non small; ki67; small cell ... See more keywords
The prognostic significance of circulating tumor cells in head and neck and non‐small‐cell lung cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1832
Abstract: Tumor biopsy is the gold standard for the assessment of clinical biomarkers for treatment. However, tumors change dynamically in response to therapy, and there remains a need for a more representative biomarker that can be… read more here.
Keywords: tumor cells; circulating tumor; head neck; cancer ... See more keywords
An integrated enrichment system to facilitate isolation and molecular characterization of single cancer cells from whole blood
Sign Up to like & getrecommendations! Published in 2018 at "Cytometry Part A"
DOI: 10.1002/cyto.a.23599
Abstract: Circulating tumor cells (CTCs) carry valuable biological information. While enumeration of CTCs in peripheral blood is an FDA‐approved prognostic indicator of survival in metastatic prostate and other cancers, analysis of CTC phenotypic and genomic markers… read more here.
Keywords: system; blood; cancer cells; cancer ... See more keywords
Cytomorphologic visualization of circulating tumor cells in urinary bladder cancer patients using ScreenCell™ technology: Potential as a simple cytology test
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostic Cytopathology"
DOI: 10.1002/dc.25141
Abstract: Circulating tumor cells (CTC) are a recent technique which is a potentially important prognostic factor in many solid tumors. There are many techniques of detecting CTCs, but they usually implement costly techniques like EpCAM targeted… read more here.
Keywords: circulating tumor; tumor cells; ctcs; cytology ... See more keywords
RhoA‐stimulated intra‐capillary morphology switch facilitates the arrest of individual circulating tumor cells
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31238
Abstract: Metastasis is the primary cause of death for most cancer patients. Hematogenous arrest of circulating tumor cells (CTCs) is an essential prerequisite for metastases formation. Using transparent transgenic zebrafish (kdrl:eGFP; Casper), together with resonant laser… read more here.
Keywords: arrest individual; tumor cells; intra capillary; circulating tumor ... See more keywords
Utilizing Matrigel Transwell Invasion Assay to Detect and Enumerate Circulating Tumor Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7144-2_23
Abstract: Metastasis is the cause of 90% of human cancer deaths. Circulating tumor cells (CTCs) in the peripheral blood and/or lymphatic vessels are cells shed from primary tumors and considered to be precursors of metastasis. Study… read more here.
Keywords: tumor cells; circulating tumor; detect enumerate; ctcs ... See more keywords
Molecular Profiling and Significance of Circulating Tumor Cell Based Genetic Signatures.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-55947-6_8
Abstract: Cancer kills by metastasizing beyond the primary site. Early detection, surgical intervention and other treatments have improved the survival rates of patients with cancer, however, once metastasis occurs, responses to conventional therapies become significantly less… read more here.
Keywords: tumor cells; genetic signatures; circulating tumor; cancer ... See more keywords
18F-FDG PET/CT and circulating tumor cells in treatment-naive patients with non-small-cell lung cancer
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-021-05260-z
Abstract: This study retrospectively investigated the clinical utility of 2-deoxy-18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) and circulating tumor cells (CTCs) in the diagnosis and prognosis of treatment-naive patients with non-small-cell lung cancer (NSCLC). The blood… read more here.
Keywords: naive patients; fdg pet; 18f fdg; treatment naive ... See more keywords
Epithelial circulating tumor cells with a heterogeneous phenotype are associated with metastasis in NSCLC
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-021-03681-9
Abstract: To analyze the clinical relevance of heterogeneous phenotypes of peripheral circulating tumor cells (CTCs) in non-small cell lung cancer (NSCLC). CTCs in 5 mL venous blood were enriched using the Canpatrol™ CTC technique in 82… read more here.
Keywords: phenotype; tumor cells; metastasis; circulating tumor ... See more keywords
Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study
Sign Up to like & getrecommendations! Published in 2017 at "Investigational New Drugs"
DOI: 10.1007/s10637-017-0446-z
Abstract: SummaryBackground Circulating tumor cells (CTCs) and chemokine (C-X-C motif) receptor 4 (CXCR4) expression in CTCs and tumor tissue were evaluated as prognostic or predictive markers of CXCR4 peptide antagonist LY2510924 plus carboplatin-etoposide (CE) versus CE… read more here.
Keywords: cxcr4 expression; prognostic predictive; ctcs; tumor ... See more keywords
The role of circulating tumor cells and K-ras mutations in patients with locally advanced rectal cancer: a prospective study.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular biology reports"
DOI: 10.1007/s11033-020-05973-8
Abstract: Rectal cancer is a common malignancy with a relatively poor prognosis. We assessed the possible prognostic and predictive role(s) of circulating tumor cells (CTCs) and K-ras mutations in locally advanced rectal carcinoma (LARC) patients. CTCs… read more here.
Keywords: rectal cancer; role circulating; ras mutations; circulating tumor ... See more keywords