Integration of ALV into CTDSPL and CTDSPL2 genes in B-cell lymphomas promotes cell immortalization, migration and survival.
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DOI: 10.18632/oncotarget.19328
Abstract: Avian leukosis virus induces tumors in chickens by integrating into the genome and altering expression of nearby genes. Thus, ALV can be used as an insertional mutagenesis tool to identify novel genes involved in tumorigenesis.… read more here.
Keywords: integration; ctdspl ctdspl2; cell lymphomas; migration ... See more keywords