LncRNA TUG1 Acts as a Competing Endogenous RNA to Mediate CTGF Expression by Sponging miR-133b in Myocardial Fibrosis after Myocardial Infarction.
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DOI: 10.1002/cbin.11707
Abstract: Myocardial fibrosis is one of the basic causes of many cardiovascular diseases. Noncoding RNAs (ncRNAs), including microRNA (miRNA) and long noncoding RNA (lncRNA), have been reported to play an indispensable role in myocardial fibrosis. The… read more here.
Keywords: mir 133b; myocardial fibrosis; expression; ctgf ... See more keywords
Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease
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DOI: 10.1002/hep.32777
Abstract: Background and Aims: Detailed investigation of the biological pathways leading to hepatic fibrosis and identification of liver fibrosis biomarkers may facilitate early interventions for pediatric cholestasis. Approach and Results: A targeted enzyme‐linked immunosorbent assay–based panel… read more here.
Keywords: correlated liver; disease; ctgf; liver stiffness ... See more keywords
Protection of CTGF Antibody Against Diabetic Nephropathy in Mice Via Reducing Glomerular β‐Catenin Expression and Podocyte Epithelial‐Mesenchymal Transition
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DOI: 10.1002/jcb.26017
Abstract: Despite substantial progress in medical care, the morbidity rate of diabetic nephropathy (DN) remains high in patients with diabetes. Evidence suggests that connective tissue growth factor (CTGF) induced podocyte injury may contribute to DN and… read more here.
Keywords: ctgf antibody; catenin expression; antibody; mice ... See more keywords
TGFβ mediates collagen production in human CRSsNP nasal mucosa‐derived fibroblasts through Smad2/3‐dependent pathway and CTGF induction and secretion
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DOI: 10.1002/jcp.27718
Abstract: Chronic rhinosinusitis without nasal polyp (CRSsNP) is characterized by tissue remodeling and fibrosis. Transforming growth factor‐β (TGF‐β) is considered a master switch in the induction of the profibrotic program which can induce fibroblasts to synthesize… read more here.
Keywords: tgf; expression; ctgf; crssnp nasal ... See more keywords
Transdermal peptide conjugated to human connective tissue growth factor with enhanced cell proliferation and hyaluronic acid synthesis activities produced by a silkworm silk gland bioreactor.
Sign Up to like & getrecommendations! Published in 2020 at "Applied microbiology and biotechnology"
DOI: 10.1007/s00253-020-10836-0
Abstract: Human connective tissue growth factor (CTGF) is a secreted cysteine-rich peptide that stimulates cell proliferation, migration, and extracellular matrix production during tissue development, differentiation, angiogenesis, implantation, wound healing, and fibrosis processes, with broad application in… read more here.
Keywords: tissue growth; cell proliferation; connective tissue; tissue ... See more keywords
Epigenetic activation of CTGF transcription by high glucose in renal tubular epithelial cells is mediated by myocardin-related transcription factor A
Sign Up to like & getrecommendations! Published in 2019 at "Cell and Tissue Research"
DOI: 10.1007/s00441-019-03124-5
Abstract: Diabetic nephropathy (DN) is one of the most devastating complications of diabetes. Connective tissue growth factor (CTGF) levels are up-regulated in patients with DN and in renal tubular epithelial cells (RTECs) exposed to high glucose… read more here.
Keywords: transcription; factor; renal tubular; tubular epithelial ... See more keywords
Isolation and characterization of hypoxia inducible gene connective tissue growth factor (CTGF) in Labeo rohita
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DOI: 10.1007/s11033-019-04617-w
Abstract: The connective tissue growth factor gene plays important role in several biological processes and also responsive to hypoxia stress in fishes. The freshwater fish, Labeo rohita, highly cultured in Indian subcontinent for food, is reported… read more here.
Keywords: ctgf gene; tissue growth; connective tissue; ctgf ... See more keywords
Association of Plasma Connective Tissue Growth Factor Levels with Hyperthyroid Heart Disease
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DOI: 10.1007/s11596-021-2354-x
Abstract: Hyperthyroid heart disease (HHD) is one of the most severe complications of overt hyperthyroidism and increases the risk of mortality in affected patients. Early identification of patients at a higher risk of developing HHD can… read more here.
Keywords: risk; plasma ctgf; hyperthyroid heart; ctgf ... See more keywords
HIV Tat Protein Induces Myocardial Fibrosis Through TGF-β1-CTGF Signaling Cascade: A Potential Mechanism of HIV Infection-Related Cardiac Manifestations.
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DOI: 10.1007/s12012-021-09687-6
Abstract: Human immunodeficiency virus (HIV) infection is a risk factor of cardiovascular diseases (CVDs). HIV-infected patients exhibit cardiac dysfunction coupled with cardiac fibrosis. However, the reason why HIV could induce cardiac fibrosis remains largely unexplored. HIV-1… read more here.
Keywords: protein; fibrosis; mouse cardiac; hiv ... See more keywords
Stem cells from human exfoliated deciduous teeth transmit microRNA-26a to protect rats with experimental intracerebral hemorrhage from cerebral injury via suppressing CTGF
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DOI: 10.1016/j.brainresbull.2020.12.006
Abstract: OBJECTIVE A large number of studies have shown that stem cells from human exfoliated deciduous teeth (SHED) has a protective effect on brain damage, but its specific mechanism is unclear. This research focused on the… read more here.
Keywords: mir 26a; expression; ctgf; injury ... See more keywords
Connective tissue growth factor regulates fibrosis-associated renal lymphangiogenesis.
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DOI: 10.1016/j.kint.2017.03.029
Abstract: Lymphangiogenesis is correlated with the degree of renal interstitial fibrosis. Pro-fibrotic transforming growth factor β induces VEGF-C production, the main driver of lymphangiogenesis. Connective tissue growth factor (CTGF) is an important determinant of fibrotic tissue remodeling,… read more here.
Keywords: lymphangiogenesis; growth factor; ctgf; fibrosis associated ... See more keywords