IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients
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DOI: 10.1080/2162402x.2016.1261242
Abstract: ABSTRACT Despite the success of immune checkpoint blockade in melanoma, the majority of patients do not respond. We hypothesized that the T and NK cell subset frequencies and expression levels of their receptors may predict… read more here.
Keywords: melanoma; tim cells; anti ctla; treatment ... See more keywords
Abstract 6679: Immunophenotypic and transcriptome analyses of CT26 and 4T1 murine tumor models following anti-CTLA-4 treatment
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DOI: 10.1158/1538-7445.am2020-6679
Abstract: Model selection for evaluation of immuno-oncology agents is often aided by both response to therapy and changes in immune cell subsets following treatment. To identify underlying factors that influence differences in therapeutic response, CT26 colorectal… read more here.
Keywords: anti ctla; treatment; ct26; cell ... See more keywords