USP33 enhances cell survival and stemness by deubiquitinating CTNNB1 in BXPC-3 and SW1990 cells.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12024
Abstract: Ubiquitin-specific protease 33 (USP33) has been implicated in various cancers, but its biological function and mechanism of action remain unknown in pancreatic cancer (PCa) as a deubiquitinating enzyme. Herein, we report that USP33 silencing inhibits… read more here.
Keywords: cell; bxpc; pca; sw1990 ... See more keywords
Phoenixin-14 regulates proliferation and apoptosis of vascular smooth muscle cells by modulation of KCNQ1OT1/miR-183-3p/CTNNB1 axis.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2021.103655
Abstract: Phoenixin-14 was reported to be implicated in the process of blood glucose metabolism, reproduction, lipid deposition and cardioprotection. However, the role of phoenixin-14 has not been investigated in vascular smooth muscle cells (VSMCs). In this… read more here.
Keywords: mir 183; proliferation apoptosis; vascular smooth; phoenixin ... See more keywords
Goat CTNNB1: mRNA expression profile of alternative splicing in testis and association analysis with litter size.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.08.061
Abstract: Catenin beta 1 (CTNNB1, also known as β-catenin), is a key gene involved in wnt-β-catenin signaling pathway and plays a significant role in animal reproduction. The aim of this study was to explore the expression… read more here.
Keywords: testis; litter size; expression; association analysis ... See more keywords
Is immunohistochemical staining for β-catenin the definitive pathological diagnostic tool for desmoid-type fibromatosis? A multi-institutional study.
Sign Up to like & getrecommendations! Published in 2019 at "Human pathology"
DOI: 10.1016/j.humpath.2018.09.018
Abstract: Immunohistochemical staining with anti-β-catenin antibody has been applied as a diagnostic tool for desmoid-type fibromatoses (DFs). In recent years, specific gene mutation (CTNNB1) analysis has also been reported to be useful for diagnosis of DF;… read more here.
Keywords: immunohistochemical staining; catenin; staining catenin; type ... See more keywords
Comprehensive assessment and meta-analysis of the association between CTNNB1 polymorphisms and cancer risk
Sign Up to like & getrecommendations! Published in 2017 at "Bioscience Reports"
DOI: 10.1042/bsr20171121
Abstract: CTNNB1, encoding β-catenin, is a well-known tumor-related gene in the wnt signaling pathway. It has been reported that CTNNB1 polymorphisms are associated with cancer risk. However, the data were inconsistent. In this article, we conducted… read more here.
Keywords: risk; analysis; association; cancer risk ... See more keywords
49 Expression and actions of the dickkopf-1 receptors KREMEN1 and KREMEN2 in the bovine pre-implantation embryo
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction, Fertility and Development"
DOI: 10.1071/rdv32n2ab49
Abstract: Dickkopf-1 (DKK1) is a secreted inhibitor of canonical WNT signaling expressed in the endometrium that can increase the competence of bovine blastocysts to establish pregnancy after transfer into recipients. The mechanism by which DKK1 regulates… read more here.
Keywords: cell; expression; kremen1 kremen2; cell cell ... See more keywords
Polymorphism in the 5ʹ regulatory region of CTNNB1 gene and association with age at first lay and egg production
Sign Up to like & getrecommendations! Published in 2022 at "British Poultry Science"
DOI: 10.1080/00071668.2022.2042484
Abstract: ABSTRACT 1. The Wnt signalling pathway is centred on the fact that catenin beta-1(CTNNB1) participates in the regulation of ovarian follicle development. The aim of the following study was to identify polymorphisms in the 5ʹ… read more here.
Keywords: regulatory region; ctnnb1; ctnnb1 gene; egg production ... See more keywords
TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation
Sign Up to like & getrecommendations! Published in 2019 at "Autophagy"
DOI: 10.1080/15548627.2019.1586250
Abstract: ABSTRACT Aberrant CTNNB1 signaling is one of the fundamental processes in cancers, especially colorectal cancer (CRC). Here, we reported that TRAF6, an E3 ubiquitin ligase important for inflammatory signaling, inhibited epithelial-mesenchymal transition (EMT) and CRC… read more here.
Keywords: degradation; traf6; colorectal cancer; crc ... See more keywords
The interplay of aryl hydrocarbon receptor/WNT/CTNNB1/Notch signaling pathways regulate amyloid beta precursor mRNA/protein expression and effected the learning and memory of mice.
Sign Up to like & getrecommendations! Published in 2022 at "Toxicology research"
DOI: 10.1093/toxres/tfab120
Abstract: The amyloid beta precursor protein (APP) plays a pathophysiological role in the development of Alzheimer's disease as well as a physiological role in neuronal growth and synaptogenesis. The aryl hydrocarbon receptor (AhR)/WNT/Catenin Beta 1 (CTNNB1)/Notch… read more here.
Keywords: ctnnb1 notch; ctnnb1; expression; mice ... See more keywords
Clinicopathologic and Immunohistochemical Correlates of CTNNB1 Mutated Endometrial Endometrioid Carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000583
Abstract: Endometrial endometrioid carcinomas (EECs) with exon 3 CTNNB1 mutations characterize a more aggressive subset of tumors in patients with low-grade low-stage disease. Thus, prospectively identifying these cases may be clinically relevant. The aim of this… read more here.
Keywords: catenin; ctnnb1 mutated; endometrial endometrioid; ctnnb1 ... See more keywords
Clinicopathologic Evaluation of CTNNB1 Mutations in High-Intermediate Risk Endometrial Endometrioid Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Gynecological Pathology"
DOI: 10.1097/pgp.0000000000000865
Abstract: CTNNB1 mutations convey increased risk of recurrence in low-risk endometrial endometrioid carcinoma (EEC). Results from previous high-intermediate risk (HIR) cohorts are mixed. The aims of this study were to correlate CTNNB1 mutational status with clinical… read more here.
Keywords: endometrial endometrioid; recurrence; risk; risk endometrial ... See more keywords