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Decreased Expression of the Slc31a1 Gene and Cytoplasmic Relocalization of Membrane CTR1 Protein in Renal Epithelial Cells: A Potent Protective Mechanism against Copper Nephrotoxicity in a Mouse Model of Menkes Disease

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231911441

Abstract: Kidneys play an especial role in copper redistribution in the organism. The epithelial cells of proximal tubules perform the functions of both copper uptake from the primary urine and release to the blood. These cells… read more here.

Keywords: copper; expression slc31a1; ctr1; ctr1 protein ... See more keywords