C1q/tumor necrosis factor‐related protein 9 protects cultured chondrocytes from IL‐1β‐induced inflammatory injury by inhibiting NLRP3 inflammasome activation via the AdipoR1/AMPK axis
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23452
Abstract: C1q/tumor necrosis factor‐related protein 9 (CTRP9) has been identified as a novel anti‐inflammatory factor that participates in numerous pathological conditions. However, whether CTRP9 participates in the regulation of osteoarthritis has not been studied. This work… read more here.
Keywords: ctrp9; nlrp3 inflammasome; cultured chondrocytes; adipor1 ampk ... See more keywords
Serum C1q/TNF‐related protein 9 is not related to nonalcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2018.04.019
Abstract: HighlightsThis is the first study regarding the role of circulating CTRP9 in NAFLD.Serum CTRP9 level was not different among the ultrasonographic degrees of NAFLD.Serum CTRP9 was not independently associated with NAFLD.Serum CTRP9 was independently and… read more here.
Keywords: tnf related; serum ctrp9; related protein; c1q tnf ... See more keywords
C1q/TNF‐related protein‐9 attenuates retinal inflammation and protects blood–retinal barrier in db/db mice
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2019.04.012
Abstract: ABSTRACT C1q/TNF‐related protein‐9(CTRP9) is an adipose cytokine, a closest adiponectin paralog, which has anti‐inflammatory, antioxidant, vasodilation and anti‐atherosclerosis effects. In addition, it can increase insulin sensitivity, decrease blood glucose level and inhibit the apoptosis of… read more here.
Keywords: retinal barrier; protein; blood retinal; c1q tnf ... See more keywords
C1q/TNF-related protein-9 alleviates airway inflammation in asthma.
Sign Up to like & getrecommendations! Published in 2020 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2020.106238
Abstract: BACKGROUNDS Asthma is characterized as inflammatory disorder in the respiratory system with increasing tendency. Most of the asthma patients suffered from the disease since childhood. Thus, developing novel therapeutic targets of childhood asthma is necessary.… read more here.
Keywords: ctrp9; asthma patients; airway inflammation; related protein ... See more keywords
CTRP9 alleviates foam cells apoptosis by enhancing cholesterol efflux
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.111138
Abstract: The apoptosis of foam cells leads to instability of atherosclerotic plaques. This study was designed to explore the protective role of CTRP9 in foam cell apoptosis. In our experiment, CTRP9 alleviated foam cell apoptosis. Meanwhile,… read more here.
Keywords: foam cells; ctrp9; cholesterol efflux; apoptosis ... See more keywords
Ctrp9 and adiponectin receptors in Nile tilapia (Oreochromis niloticus): Molecular cloning, tissue distribution and effects on reproductive genes.
Sign Up to like & getrecommendations! Published in 2018 at "General and comparative endocrinology"
DOI: 10.1016/j.ygcen.2018.05.033
Abstract: As the close paralog of adiponectin, C1q/TNF-Related Protein 9 (CTRP9) has been reported to be involved in the regulation of glucose and fat metabolism, immunization and endothelial cell functions. However, information regarding the actions of… read more here.
Keywords: ctrp9 adiponectin; tissue distribution; adipor1 adipor2; ctrp9 ... See more keywords
Increased Levels of ANGPTL3 and CTRP9 in Patients With Obstructive Sleep Apnea and Their Relation to Insulin Resistance and Lipid Metabolism and Markers of Endothelial Dysfunction.
Sign Up to like & getrecommendations! Published in 2022 at "Laboratory medicine"
DOI: 10.1093/labmed/lmac073
Abstract: OBJECTIVE Obstructive sleep apnea (OSA) has a close relation with obesity and perturbation in adipokines and hepatokines, which are linked to OSA consequences such as insulin resistance, dyslipidemia, and endothelial dysfunction. This study aimed to… read more here.
Keywords: insulin resistance; relation; ctrp9; angptl3 ctrp9 ... See more keywords
Angiogenic adipokine C1q-TNF-related protein 9 ameliorates myocardial infarction via histone deacetylase 7-mediated MEF2 activation.
Sign Up to like & getrecommendations! Published in 2022 at "Science advances"
DOI: 10.1126/sciadv.abq0898
Abstract: C1q/tumor necrosis factor-related protein 9 (CTRP9) is an adipokine and has high potential as a therapeutic target. However, the role of CTRP9 in cardiovascular disease pathogenesis remains unclear. We found CTRP9 to induce HDAC7 and… read more here.
Keywords: related protein; infarction; c1q tnf; adipokine c1q ... See more keywords
Response by Ma et al to Letter Regarding Article, "miRNA-Mediated Suppression of a Cardioprotective Cardiokine As a Novel Mechanism Exacerbating Post-MI Remodeling by Sleep Breathing Disorders".
Sign Up to like & getrecommendations! Published in 2020 at "Circulation Research"
DOI: 10.1161/circresaha.120.317133
Abstract: In Response: We thank Dr Wang and colleagues for their interest in and comments regarding our article.1 Wang and colleagues raise 2 concerns and present several excellent comments/suggestions. Specifically, they note that reduced miR-214-3p in… read more here.
Keywords: response; post; ischemic heart; heart ... See more keywords
Down-Regulation of miR-34a-5p Potentiates Protective Effect of Adipose-Derived Mesenchymal Stem Cells Against Ischemic Myocardial Infarction by Stimulating the Expression of C1q/Tumor Necrosis Factor-Related Protein-9
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.01445
Abstract: Adipose-derived stem cells (ADSCs) have shown great promise for the treatment of myocardial infarction (MI), although their potential therapeutic mechanism remains poorly understood. Growing evidence has implicated microRNAs (miRNAs or miRs) in the biological processes… read more here.
Keywords: mir 34a; expression; stem; factor ... See more keywords
C1q/Tumor Necrosis Factor-Related Protein 9: Basics and Therapeutic Potentials
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.816218
Abstract: C1q/tumor necrosis factor-related protein 9 (CTRP9) is a newly discovered adipokine that is the closest paralog of adiponectin. Proteolytic cleavage of CTRP9 leads to the release of the globular domain (gCTRP9), which serves as the… read more here.
Keywords: c1q tumor; necrosis factor; related protein; tumor necrosis ... See more keywords