Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660)
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Clinical Pharmacology"
DOI: 10.1111/bcp.13398
Abstract: AIMS Cathepsin C (CTSC) is necessary for the activation of several serine proteases including neutrophil elastase (NE), cathepsin G and proteinase 3. GSK2793660 is an oral, irreversible inhibitor of CTSC that is hypothesized to provide… read more here.
Keywords: inhibitor; ctsc; cathepsin; phase study ... See more keywords