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   Articles with "ctx" as a keyword



Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

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recommendations! Published in 2017 at "Peptide Science"

DOI: 10.1002/bip.23025

Abstract: Chlorotoxin (CTX), a disulfide‐rich peptide from the scorpion Leiurus quinquestriatus, has several promising biopharmaceutical properties, including preferential affinity for certain cancer cells, high serum stability, and cell penetration. These properties underpin its potential for use… read more here.

Keywords: ctx; arginine mutagenesis; lysine arginine; mutagenesis chlorotoxin ... See more keywords

Bone Turnover Markers Including Undercarboxylated Osteocalcin Are Associated With Mortality Risk in Older Men

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recommendations! Published in 2022 at "Journal of Bone and Mineral Research"

DOI: 10.1002/jbmr.4631

Abstract: Osteocalcin in its undercarboxylated form (ucOC) may influence diabetes risk; however, its relationship with all‐cause and cause‐specific mortality is unclear. Whether other bone turnover markers (BTMs) are associated with mortality risk differently from ucOC also… read more here.

Keywords: cause; mortality; ctx; bone turnover ... See more keywords

Asperuloside alleviates cyclophosphamide‐induced myelosuppression by promoting AMPK/mTOR pathway‐mediated autophagy

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recommendations! Published in 2024 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.23641

Abstract: Cyclophosphamide (CTX) is a common anticancer chemotherapy drug, and myelosuppression is the most common serious side effect. Asperuloside (ASP), the active component of Hedyotis diffusa Willd., may have the effect of ameliorating chemotherapy‐induced myelosuppression. This… read more here.

Keywords: ctx; myelosuppression; mtor pathway; induced myelosuppression ... See more keywords

Human BDNF rs6265 polymorphism as a mediator for the generalization of contextual anxiety

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recommendations! Published in 2019 at "Journal of Neuroscience Research"

DOI: 10.1002/jnr.24345

Abstract: The Met allele of the human brain‐derived neurotrophic factor (BDNF) gene might be a risk factor for anxiety disorders and is associated with reduced hippocampal volume. Notably, hippocampus plays a crucial role in contextual learning… read more here.

Keywords: generalization; anxiety; ctx; met allele ... See more keywords

Isolation of extended‐spectrum β‐lactamase‐producing Escherichia coli from Japanese red fox (Vulpes vulpes japonica)

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recommendations! Published in 2022 at "MicrobiologyOpen"

DOI: 10.1002/mbo3.1317

Abstract: Antimicrobial resistance is a global concern requiring a one‐health approach. Given wild animals can harbor antimicrobial‐resistant bacteria (ARB), we investigated their presence in 11 fecal samples from wild animals using deoxycholate hydrogen sulfide lactose agar… read more here.

Keywords: escherichia coli; spectrum lactamase; japanese red; red fox ... See more keywords

Encapsulating Ni Nanoparticles into Interlayers of Nitrogen-Doped Nb2 CTx MXene to Boost Hydrogen Evolution Reaction in Acid.

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recommendations! Published in 2022 at "Small"

DOI: 10.1002/smll.202206098

Abstract: Design and development of low-cost and highly efficient non-precious metal electrocatalysts for hydrogen evolution reaction (HER) in an acidic medium are key issues to realize the commercialization of proton exchange membrane water electrolyzers. Ni is… read more here.

Keywords: ctx mxene; doped nb2; nb2 ctx; ctx ... See more keywords

The M1/M2 Macrophage Polarization and Hepatoprotective Activity of Quercetin in Cyclophosphamide‐Induced Experimental Liver Toxicity

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recommendations! Published in 2025 at "Veterinary Medicine and Science"

DOI: 10.1002/vms3.70183

Abstract: ABSTRACT Background Chemotherapy drugs may lead to hepatic injury, which is considered one of the limitations of these drugs. Objectives The aim of this study was to evaluate the effect of quercetin (QUE) on M1/M2… read more here.

Keywords: ctx; que; macrophage polarization; liver ... See more keywords

Prevalence and antimicrobial susceptibility of CTX‐M‐type‐producing Escherichia coli from a wildlife zoo in China

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recommendations! Published in 2022 at "Veterinary Medicine and Science"

DOI: 10.1002/vms3.773

Abstract: Abstract Background Wildlife zoos provide the opportunity for children and adults to interact with animals, However, it's unknown that the risk of contact with animals, which carried zoonotic pathogens and antimicrobial resistant bacteria. Objectives This… read more here.

Keywords: prevalence antimicrobial; bla ctx; ctx; wildlife zoo ... See more keywords

Autism spectrum disorder: an early and frequent feature in cerebrotendinous xanthomatosis

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recommendations! Published in 2017 at "Journal of Inherited Metabolic Disease"

DOI: 10.1007/s10545-017-0086-7

Abstract: BackgroundCerebrotendinous xanthomatosis (CTX) is an autosomal recessively inherited inborn error of metabolism (IEM) due to mutations in the CYP27A1 gene. The clinical picture ranges from being nearly asymptomatic in early childhood, up to severe disability… read more here.

Keywords: frequent feature; xanthomatosis; ctx; spectrum disorder ... See more keywords

PEGylated lipid microspheres loaded with cabazitaxel for intravenous administration: stability, bioavailability, antitumor efficacy, and toxicity

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recommendations! Published in 2018 at "Drug Delivery and Translational Research"

DOI: 10.1007/s13346-018-0562-0

Abstract: This paper aimed to develop a novel lipid microsphere delivering cabazitaxel (CTX) using phosphatidylcholine combined with DSPE-PEG2000 as emulsifier, and evaluate its stability, pharmacokinetics, antitumor efficacy, and toxicity. The pegylated cabazitaxel-loaded lipid microspheres (CTX-PLMs) were… read more here.

Keywords: antitumor efficacy; ctx; toxicity; ctx plms ... See more keywords

Developmental toxicity and molecular responses of marine medaka (Oryzias melastigma) embryos to ciguatoxin P-CTX-1 exposure.

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recommendations! Published in 2017 at "Aquatic toxicology"

DOI: 10.1016/j.aquatox.2017.02.006

Abstract: Ciguatoxins are produced by toxic benthic dinoflagellates and cause ciguatera fish poisoning worldwide, but the toxic effects on developing marine fish have not been well investigated. The Pacific ciguatoxin (P-CTX-1), is a potent sodium channel… read more here.

Keywords: marine medaka; ctx; development; ciguatoxin ctx ... See more keywords