Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake
Sign Up to like & getrecommendations! Published in 2017 at "Peptide Science"
DOI: 10.1002/bip.23025
Abstract: Chlorotoxin (CTX), a disulfide‐rich peptide from the scorpion Leiurus quinquestriatus, has several promising biopharmaceutical properties, including preferential affinity for certain cancer cells, high serum stability, and cell penetration. These properties underpin its potential for use… read more here.
Keywords: ctx; arginine mutagenesis; lysine arginine; mutagenesis chlorotoxin ... See more keywords
Bone Turnover Markers Including Undercarboxylated Osteocalcin Are Associated With Mortality Risk in Older Men
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4631
Abstract: Osteocalcin in its undercarboxylated form (ucOC) may influence diabetes risk; however, its relationship with all‐cause and cause‐specific mortality is unclear. Whether other bone turnover markers (BTMs) are associated with mortality risk differently from ucOC also… read more here.
Keywords: cause; mortality; ctx; bone turnover ... See more keywords
Human BDNF rs6265 polymorphism as a mediator for the generalization of contextual anxiety
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24345
Abstract: The Met allele of the human brain‐derived neurotrophic factor (BDNF) gene might be a risk factor for anxiety disorders and is associated with reduced hippocampal volume. Notably, hippocampus plays a crucial role in contextual learning… read more here.
Keywords: generalization; anxiety; ctx; met allele ... See more keywords
Isolation of extended‐spectrum β‐lactamase‐producing Escherichia coli from Japanese red fox (Vulpes vulpes japonica)
Sign Up to like & getrecommendations! Published in 2022 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1317
Abstract: Antimicrobial resistance is a global concern requiring a one‐health approach. Given wild animals can harbor antimicrobial‐resistant bacteria (ARB), we investigated their presence in 11 fecal samples from wild animals using deoxycholate hydrogen sulfide lactose agar… read more here.
Keywords: escherichia coli; spectrum lactamase; japanese red; red fox ... See more keywords
Encapsulating Ni Nanoparticles into Interlayers of Nitrogen-Doped Nb2 CTx MXene to Boost Hydrogen Evolution Reaction in Acid.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202206098
Abstract: Design and development of low-cost and highly efficient non-precious metal electrocatalysts for hydrogen evolution reaction (HER) in an acidic medium are key issues to realize the commercialization of proton exchange membrane water electrolyzers. Ni is… read more here.
Keywords: ctx mxene; doped nb2; nb2 ctx; ctx ... See more keywords
Prevalence and antimicrobial susceptibility of CTX‐M‐type‐producing Escherichia coli from a wildlife zoo in China
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.773
Abstract: Abstract Background Wildlife zoos provide the opportunity for children and adults to interact with animals, However, it's unknown that the risk of contact with animals, which carried zoonotic pathogens and antimicrobial resistant bacteria. Objectives This… read more here.
Keywords: prevalence antimicrobial; bla ctx; ctx; wildlife zoo ... See more keywords
Autism spectrum disorder: an early and frequent feature in cerebrotendinous xanthomatosis
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Inherited Metabolic Disease"
DOI: 10.1007/s10545-017-0086-7
Abstract: BackgroundCerebrotendinous xanthomatosis (CTX) is an autosomal recessively inherited inborn error of metabolism (IEM) due to mutations in the CYP27A1 gene. The clinical picture ranges from being nearly asymptomatic in early childhood, up to severe disability… read more here.
Keywords: frequent feature; xanthomatosis; ctx; spectrum disorder ... See more keywords
PEGylated lipid microspheres loaded with cabazitaxel for intravenous administration: stability, bioavailability, antitumor efficacy, and toxicity
Sign Up to like & getrecommendations! Published in 2018 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-018-0562-0
Abstract: This paper aimed to develop a novel lipid microsphere delivering cabazitaxel (CTX) using phosphatidylcholine combined with DSPE-PEG2000 as emulsifier, and evaluate its stability, pharmacokinetics, antitumor efficacy, and toxicity. The pegylated cabazitaxel-loaded lipid microspheres (CTX-PLMs) were… read more here.
Keywords: antitumor efficacy; ctx; toxicity; ctx plms ... See more keywords
Developmental toxicity and molecular responses of marine medaka (Oryzias melastigma) embryos to ciguatoxin P-CTX-1 exposure.
Sign Up to like & getrecommendations! Published in 2017 at "Aquatic toxicology"
DOI: 10.1016/j.aquatox.2017.02.006
Abstract: Ciguatoxins are produced by toxic benthic dinoflagellates and cause ciguatera fish poisoning worldwide, but the toxic effects on developing marine fish have not been well investigated. The Pacific ciguatoxin (P-CTX-1), is a potent sodium channel… read more here.
Keywords: marine medaka; ctx; development; ciguatoxin ctx ... See more keywords
Calcineurin inhibitors versus cyclophosphamide for idiopathic membranous nephropathy: A systematic review and meta-analysis of 21 clinical trials.
Sign Up to like & getrecommendations! Published in 2017 at "Autoimmunity reviews"
DOI: 10.1016/j.autrev.2016.12.005
Abstract: OBJECTIVE To compare the efficacy and safety of calcineurin inhibitors (CNIs) with cyclophosphamide (CTX) in the treatment of idiopathic membranous nephropathy (IMN). METHODS A literature search was carried out using PubMed, EMBASE, Cochrane Central Register… read more here.
Keywords: calcineurin inhibitors; tac ctx; efficacy safety; ctx ... See more keywords
Novel Serological Biomarker Models Composed of Bone Turnover Markers, Vitamin D, and Estradiol and Their Auxiliary Diagnostic Value in Girls with Idiopathic Central Precocious Puberty.
Sign Up to like & getrecommendations! Published in 2021 at "Bone"
DOI: 10.1016/j.bone.2021.116221
Abstract: OBJECTIVE To establish serological biomarker models composed of bone turnover markers (BTMs), vitamin D (Vit D), and estradiol (E2) and to explore their auxiliary diagnostic value in girls with idiopathic central precocious puberty (ICPP). METHODS… read more here.
Keywords: ctx; biomarker models; vit; p1np ctx ... See more keywords