Articles with "ctz" as a keyword



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Near-Infrared Bioluminescence Imaging of Animal Cells with Through-Bond Energy Transfer Cassette.

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Published in 2021 at "Methods in molecular biology"

DOI: 10.1007/978-1-0716-1258-3_10

Abstract: Coelenterazine (CTZ) is the most general substrate for marine luciferases. The present protocol introduces a near-infrared (NIR ) bioluminescence (BL) imaging of mammalian cells with a cyanine-5 (Cy5) dye-conjugated CTZ . This unique Cy5-conjugated CTZ,… read more here.

Keywords: ctz; bond energy; energy transfer; cy5 ctz ... See more keywords
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Metal–azole fungistatic drug complexes as anti-Sporothrix spp. agents

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Published in 2018 at "New Journal of Chemistry"

DOI: 10.1039/c8nj01544a

Abstract: The new complexes [Cu(PPh3)2(KTZ)2]NO3 (1), [Cu(PPh3)2(CTZ)2]NO3 (2), [Au(KTZ)2]Cl (3), [Au(CTZ)2]Cl (4) and Pt(KTZ)2Cl2 (5) were prepared by reaction of KTZ, CTZ (where CTZ: 1-[(2-chlorophenyl)-diphenylmethyl]-1H-imidazole and KTZ: cis-1-acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine) and their respective metal salts or metal complexes… read more here.

Keywords: ctz; pph3; microscopy; metal ... See more keywords
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FRI0130 Certolizumab pegol exposure during pregnancy in women with rheumatoid arthritis: evaluation of the long-term newborn outcomes

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Published in 2018 at "Annals of the Rheumatic Diseases"

DOI: 10.1136/annrheumdis-2018-eular.4632

Abstract: Background Increased TNF alpha (TNFα) levels have been associated to pregnancy complications such as intra-uterine growth retardation and fetal loss. Even if pregnancy has classically been considered as having a positive impact on RA, disease… read more here.

Keywords: ctz; pregnancy; pregnancy women; certolizumab pegol ... See more keywords
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Antidermatophytic Activity and Skin Retention of Clotrimazole Microemulsion and Microemulsion-Based Gel in Comparison to Conventional Cream

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Published in 2018 at "Skin Pharmacology and Physiology"

DOI: 10.1159/000491756

Abstract: Aim: Antifungal activity, skin permeation and skin retention of water-in-oil microemulsion (ME) and microemulsion-based gel (MBG) containing clotrimazole (CTZ) were evaluated in comparison to a conventional CTZ cream. Methods: CTZ-ME and CTZ-MBG containing 1% w/w… read more here.

Keywords: ctz; conventional cream; comparison conventional; skin ... See more keywords

Reverse mutants of the catalytic 19 kDa mutant protein (nanoKAZ/nanoLuc) from Oplophorus luciferase with coelenterazine as preferred substrate

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0272992

Abstract: Native Oplophorus luciferase (OpLase) and its catalytic 19 kDa protein (wild KAZ) show highest luminescence activity with coelenterazine (CTZ) among CTZ analogs. Mutated wild KAZ with 16 amino acid substitutions (nanoKAZ/nanoLuc) utilizes bis-coelenterazine (bis-CTZ) as… read more here.

Keywords: ctz; nanokaz nanoluc; luminescence; oplophorus luciferase ... See more keywords
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Effect of Antihypertensive Drug (Chlorothiazide) on Fibrillation of Lysozyme: A Combined Spectroscopy, Microscopy, and Computational Study

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24043112

Abstract: Amyloid fibrils abnormally accumulate together in the human body under certain conditions, which can result in lethal conditions. Thus, blocking this aggregation may prevent or treat this disease. Chlorothiazide (CTZ) is a diuretic and is… read more here.

Keywords: aggregation; spectroscopy; microscopy; amyloid ... See more keywords
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Functionally Graded Al2O3–CTZ Ceramics Fabricated by Spark Plasma Sintering

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Published in 2022 at "Materials"

DOI: 10.3390/ma15051860

Abstract: We studied the fabrication of functionally graded Al2O3–CeO2-stabilized-ZrO2 (CTZ) ceramics by spark plasma sintering. The ceramic composite exhibits a gradual change in terms of composition and porosity in the axial direction. The composition gradient was… read more here.

Keywords: graded al2o3; ctz ceramics; spark plasma; functionally graded ... See more keywords