Inhibitory potency of 4- substituted sampangine derivatives toward Cu2+ mediated aggregation of amyloid β-peptide, oxidative stress, and inflammation in Alzheimer's disease
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DOI: 10.1016/j.neuint.2020.104794
Abstract: Cu2+ plays a key role in the pathogenesis of Alzheimer's disease (AD). The dysregulation of Cu2+ can cause neuronal damage and aggravate development of AD. Moreover, a series of 4-substituted sampangine derivatives have been investigated… read more here.
Keywords: sampangine derivatives; cu2; alzheimer disease; cu2 mediated ... See more keywords