Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity.
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DOI: 10.1021/acschemneuro.2c00253
Abstract: CuATSM has repeatedly demonstrated to be therapeutically effective in SOD1 mouse models of amyotrophic lateral sclerosis (ALS), leading to current clinical trials. CuATSM acts to stabilize ALS-associated mutant SOD1 protein by supplying copper. However, in… read more here.
Keywords: copper; cuatsm associated; als associated; sod1 ... See more keywords