Down-Regulated CUEDC2 Increases GDNF Expression by Stabilizing CREB Through Reducing Its Ubiquitination in Glioma.
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DOI: 10.1007/s11064-020-03140-w
Abstract: Abnormally high expression of glial cell line-derived neurotrophic factor (GDNF) derived from glioma cells has essential impacts on gliomagenesis and development, but the molecular basis underlying increased GDNF expression in glioma cells remain unclear. This work… read more here.
Keywords: glioma; creb; expression; glioma cells ... See more keywords
Kawasaki disease: SOCS2-AS1/miR-324-5p/CUEDC2 axis regulates the progression of human umbilical vein endothelial cells
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DOI: 10.1038/s41390-020-1029-9
Abstract: Kawasaki disease (KD) is the most prevailing cause of acquired heart disease in children, due to permanent coronary artery damage. Recently, the role of long noncoding RNAs (lncRNAs) in human diseases has been highlighted. However,… read more here.
Keywords: socs2 as1; as1; huvecs; cuedc2 ... See more keywords
Comparison of ADAM19 and CUEDC2 expressions in EHCC and their clinicopathological significances.
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DOI: 10.2217/bmm-2020-0321
Abstract: Background: To evaluate the expression and clinicopathological significance of a disintegrin and metalloproteinases 19 (ADAM19) CUE domain containing protein 2 (CUEDC2) in extrahepatic cholangiocarcinoma (EHCC). Materials & methods: Immunostaining of ADAM19 and CUEDC2 was performed… read more here.
Keywords: adam19 cuedc2; expression adam19; ehcc; cuedc2 ... See more keywords
Downregulation of CUEDC2 prevents doxorubicin-induced cardiotoxicity in H9c2 cells
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DOI: 10.3892/mmr.2018.9072
Abstract: Treatment with doxorubicin (DOX), which is an effective anticancer agent, is limited by cardiotoxicity. CUE domain-containing 2 (CUEDC2) serves a role in numerous cellular processes. The present study aimed to elucidate the potential function of… read more here.
Keywords: dox induced; induced cardiotoxicity; dox; downregulation ... See more keywords