Developmental cues license megakaryocyte priming in murine hematopoietic stem cells
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DOI: 10.1182/bloodadvances.2021006861
Abstract: Key Points • The fetal-to-adult transition in HSC states is associated with a global acquisition of megakaryocytic chromatin accessibility signatures.• The developmentally restricted expression of LIN28B suppresses establishment of an Mk-biased HSC pool early in… read more here.
Keywords: megakaryocyte priming; developmental cues; murine hematopoietic; cues license ... See more keywords