Abstract P086: Endothelial Cullin3 Mutation Causes Vascular Dysfunction, Arterial Stiffening, And Hypertension
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DOI: 10.1161/hyp.76.suppl_1.p086
Abstract: Mutations in CULLIN3 gene (causing in-frame deletion of exon 9) cause hypertension in humans. The hypertension phenotype is unlikely to be driven by renal tubular mechanisms, as kidney-specific deletion of Cullin3 (Cul3) in mice results… read more here.
Keywords: dysfunction; causes vascular; hypertension; cul3 ... See more keywords