Articles with "cullin3" as a keyword



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Regulation of Rho GTPases in the Vasculature by Cullin3-Based E3 Ligase Complexes

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.680901

Abstract: Cullin3-based ubiquitin E3 ligases induce ubiquitination of substrates leading to their proteasomal or lysosomal degradation. BTB proteins serve as adaptors by binding to Cullin3 and recruiting substrate proteins, which enables specific recognition of a broad… read more here.

Keywords: ligase complexes; regulation rho; cullin3; cullin3 based ... See more keywords