Trypsin‐Free Cultivation of 3D Mini‐Tissues in an Adaptive Membrane Bioreactor
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Biosystems"
DOI: 10.1002/adbi.202000081
Abstract: The production of large scaffold‐free tissues is a key challenge in regenerative medicine. Nowadays, temperature‐responsive polymers allow intact tissue harvesting without needing proteolytic enzymes. This method is limited to tissue culture plastic with limited upscaling… read more here.
Keywords: medicine; cultivation; membrane bioreactor; trypsin free ... See more keywords
Implementation of a Fully Automated Microbial Cultivation Platform for Strain and Process Screening.
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology journal"
DOI: 10.1002/biot.201800625
Abstract: Advances in molecular biotechnology have resulted in the generation of numerous potential production strains. Because every strain can be screened under various process conditions, the number of potential cultivations is multiplied. Exploiting this potential without… read more here.
Keywords: cultivation; cultivation platform; process conditions; fully automated ... See more keywords
Capillary and microchip electrophoresis method development for amino acid monitoring during biopharmaceutical cultivation
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology Journal"
DOI: 10.1002/biot.202100325
Abstract: The increased use of biopharmaceuticals calls for improved means of bioprocess monitoring. In this work, capillary electrophoresis (CE) and microchip electrophoresis (MCE) methods were developed and applied for the analysis of amino acids (AAs) in… read more here.
Keywords: microchip electrophoresis; cultivation; analysis; amino ... See more keywords
Online optimal experimental re‐design in robotic parallel fed‐batch cultivation facilities
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26192
Abstract: We present an integrated framework for the online optimal experimental re‐design applied to parallel nonlinear dynamic processes that aims to precisely estimate the parameter set of macro kinetic growth models with minimal experimental effort. This… read more here.
Keywords: experimental design; cultivation; fed batch; optimal experimental ... See more keywords
Ultrahigh‐cell‐density heterotrophic cultivation of the unicellular green microalga Scenedesmus acuminatus and application of the cells to photoautotrophic culture enhance biomass and lipid production
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.27190
Abstract: Although production of biodiesels from microalgae is proved to be technically feasible, a commercially viable system has yet to emerge. High‐cell‐density fermentation of microalgae can be coupled with photoautotrophic cultivation to produce oils. In this… read more here.
Keywords: cultivation; cell density; heterotrophic cultivation; production ... See more keywords
Passively immobilized cyanobacteria Nostoc species BB 92.2 in a moving bed photobioreactor (MBPBR): Design, cultivation, and characterization
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28072
Abstract: The cyanobacterium Nostoc sp. BB 92.3. had shown antibacterial activity. A cultivation as biofilm, a self‐forming matrix of cells and extracellular polymeric substances, increased the antibacterial effect. A new photobioreactor system was developed that allows… read more here.
Keywords: passively immobilized; moving bed; growth; cultivation ... See more keywords
Effect of HepG2 cell 3D cultivation on the metabolism of the anabolic androgenic steroid metandienone.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3455
Abstract: The elucidation of the metabolic fate of prohibited substances is crucial for the abuse detection. The human hepatocyte cell line HepG2 can be used to study biotransformation. In order to improve this in vitro model… read more here.
Keywords: cell; cultivation; biotransformation; anabolic androgenic ... See more keywords
Ecosystem functions in mixed cropland–grassland systems influenced by soil legacies of past crop cultivation decisions
Sign Up to like & getrecommendations! Published in 2018 at "Ecosphere"
DOI: 10.1002/ecs2.2521
Abstract: As global food demand continues to grow, private landowners and agricultural managers have increased incentives to convert grasslands to expand crop production. These conversions are increasingly occurring on marginal soils susceptible to rapid degradation, which… read more here.
Keywords: ecosystem functions; soil legacies; land; cultivation ... See more keywords
Study on the development and integration of 3D‐printed optics in small‐scale productions of single‐use cultivation vessels
Sign Up to like & getrecommendations! Published in 2022 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.202100131
Abstract: Integrating optical sensors and 3D‐printed optics into single‐use (SU) cultivation vessels for customized, tailor‐made equipment could be a next big step in the bioreactor and screening platform development enabling online bioprocess monitoring. Many different parameters… read more here.
Keywords: cultivation; use cultivation; optics; single use ... See more keywords
Long‐term cultivation of human amniotic fluid stem cells: The impact on proliferative capacity and differentiation potential
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29623
Abstract: Human amniotic fluid mesenchymal stem cells (AF‐MSCs) are a valuable, easily obtainable alternative source of SCs for regenerative medicine. Usually, amounts of cells required for the translational purposes are large thus the goal of this… read more here.
Keywords: long term; term cultivation; cultivation; mscs ... See more keywords
Cultivation of Encapsulated Primary Human B Lymphocytes: A First Step towards a Bioartificial Germinal Center.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200256
Abstract: Polyelectrolyte microcapsules based on sodium cellulose sulfate (SCS) and poly-diallyl-dimethyl-ammonium chloride (PDADMAC) have previously been proposed as a suitable ex vivo microenvironment for the cultivation and differentiation of primary human T lymphocytes. Here, the same… read more here.
Keywords: cell; primary human; cultivation; human lymphocytes ... See more keywords