Physicsâinformed neural networks for biopharmaceutical cultivation processes: Consideration of varying process parameter settings
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DOI: 10.1002/bit.28851
Abstract: We present a new modeling approach for the study and prediction of important process outcomes of biotechnological cultivation processes under the influence of process parameter variations. Our model is based on physicsâinformed neural networks (PINNs)… read more here.
Keywords: process; physics informed; cultivation processes; process parameter ... See more keywords
Determination and validation of design space for mesenchymal stem cell cultivation processes using prediction intervals
Sign Up to like & getrecommendations! Published in 2025 at "Communications Biology"
DOI: 10.1038/s42003-025-08063-2
Abstract: In regenerative medicine, mesenchymal stem cells (MSCs) constitute a promising therapeutic route for many diseases. The current quality-by-design guidelines do not clearly define a framework for MSC production. Here, we suggest and experimentally validate a… read more here.
Keywords: mesenchymal stem; cultivation processes; prediction intervals; cultivation ... See more keywords