Interim Effectiveness and Safety Comparison of Bedaquiline-Containing Regimens for Treatment of Diabetic Versus Non-Diabetic MDR/XDR-TB Patients in China: A Multicenter Retrospective Cohort Study
Sign Up to like & getrecommendations! Published in 2021 at "Infectious Diseases and Therapy"
DOI: 10.1007/s40121-021-00396-9
Abstract: Introduction Diabetes mellitus (DM), a common tuberculosis (TB) comorbidity, is associated with delayed bacillary clearance during anti-TB treatment and unfavorable outcomes. Bedaquiline (BDQ), when used as part of multidrug regimen for multidrug-resistant/extensively drug-resistant tuberculosis (MDR/XDR-TB),… read more here.
Keywords: week; treatment; culture conversion; study ... See more keywords
Factors associated with sputum culture conversion in patients with pulmonary tuberculosis.
Sign Up to like & getrecommendations! Published in 2017 at "Medicina"
DOI: 10.1016/j.medici.2018.01.005
Abstract: OBJECTIVE The aim of this study was to determine what factors are associated with sputum culture conversion after 1 month of tuberculosis (TB) treatment. MATERIALS AND METHODS A total of 52 patients with new drug… read more here.
Keywords: culture conversion; treatment; conversion; tuberculosis ... See more keywords
Sputum culture conversion and its predictors among drug-resistant pulmonary tuberculosis patients in eastern Ethiopia
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DOI: 10.1093/inthealth/ihae059
Abstract: Abstract Background Evidence of time to culture conversion is used to predict the time of cure from the disease and the overall drug-resistant tuberculosis (TB) treatment duration. Even though evidence about sputum culture conversion is… read more here.
Keywords: time; conversion; sputum culture; culture ... See more keywords
1468. Culture Conversion and Mortality in Patients With Mycobacterium abscessus (MAB) Lung Disease: A Systematic Literature Review
Sign Up to like & getrecommendations! Published in 2020 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofaa439.1649
Abstract: Prognosis for patients with MAB lung disease is poor. We sought to examine the potential association between culture conversion and outcomes (progression, mortality) in patients with MAB lung disease. English-language MAB lung disease studies with… read more here.
Keywords: culture conversion; lung disease; mortality; culture ... See more keywords
Time to Culture Conversion of Bedaquiline and High-Dose Isoniazid for Drug-Resistant Tuberculosis
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DOI: 10.1093/ofid/ofac440
Abstract: Abstract Patients with multidrug-resistant tuberculosis who received regimens containing high-dose isoniazid (INHHD) had similar time to culture conversion and treatment outcomes as patients who received regimens with bedaquiline. INHHD is an inexpensive and safe medication… read more here.
Keywords: dose isoniazid; time culture; resistant tuberculosis; culture conversion ... See more keywords
Clinical Implications of Time to Culture Conversion in Mycobacterium Avium Complex Pulmonary Disease
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DOI: 10.1093/ofid/ofaf664
Abstract: Abstract Background The optimal timing for assessing treatment response in Mycobacterium avium complex pulmonary disease (MAC-PD) remains unclear. This study evaluated the association between time to culture conversion and microbiological cure. Methods We retrospectively included… read more here.
Keywords: cure; conversion; culture; culture conversion ... See more keywords
Early culture conversion is a poor marker of treatment outcome among people with HIV and drug‐resistant TB
Sign Up to like & getrecommendations! Published in 2022 at "HIV Medicine"
DOI: 10.1111/hiv.13392
Abstract: Our objective was to determine associations between early (≤2 months) culture conversion (ECC) among people with HIV and drug‐resistant tuberculosis (DRTB) in Uganda. read more here.
Keywords: people hiv; among people; hiv drug; culture conversion ... See more keywords
Fluoroquinolones in Drug-Resistant Tuberculosis: Culture Conversion and Pharmacokinetic/Pharmacodynamic Target Attainment To Guide Dose Selection
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DOI: 10.1128/aac.00279-19
Abstract: Fluoroquinolones are group A drugs in tuberculosis guidelines. We aim to compare the culture conversion between new-generation (levofloxacin and moxifloxacin) and old-generation (ciprofloxacin and ofloxacin) fluoroquinolones, develop pharmacokinetic models, and calculate target attainment for levofloxacin… read more here.
Keywords: target attainment; culture conversion; generation; culture ... See more keywords
Linezolid Experience Among MDR-TB Patients in Mumbai
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DOI: 10.1183/1393003.congress-2017.pa3486
Abstract: Background: India has 25% of the world’s tuberculosis. Mumbai is home to 12% of India’s cases that are resistant to rifampin and isoniazid (MDR-TB), but they are often resistant to standard treatment. Linezolid (LZD) resistance… read more here.
Keywords: experience among; culture conversion; lzd; mdr patients ... See more keywords
Time to sputum culture conversion and its associated factors among drug-resistant tuberculosis patients: a systematic review and meta-analysis
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DOI: 10.1186/s12879-024-09009-5
Abstract: Objective We aimed to evaluate the sputum culture conversion time of DR-TB patients and its related factors. Methods PubMed, The Cochrane Library, Embase, CINAHL, Web of Science, CNKI, Wan Fang, CBM and VIP databases were… read more here.
Keywords: history; time; sputum culture; culture ... See more keywords
Substitution of ethambutol with linezolid during the intensive phase of treatment of pulmonary tuberculosis: study protocol for a prospective, multicenter, randomized, open-label, phase II trial
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DOI: 10.1186/s13063-017-1811-0
Abstract: BackgroundLinezolid, an oxazolidinone, substantially improves treatment outcomes of multidrug-resistant tuberculosis and extensively drug-resistant tuberculosis. We started a trial to test whether the use of linezolid instead of ethambutol could increase the rate of sputum culture… read more here.
Keywords: phase; treatment; culture conversion; tuberculosis ... See more keywords