A novel 3D cell culture model to study the human small intestinal immune landscape
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250131
Abstract: Several subsets of mononuclear phagocytes and DCs (MDC) populate the small intestine (SI), and these cells reportedly exert specialized functions in anti‐microbial immunity and tolerance. Given the specialized phenotype of these cells, differing from other… read more here.
Keywords: differentiation; cell culture; cell; culture model ... See more keywords
A 3D Culture Model to Study How Fluid Pressure and Flow Affect the Behavior of Aggregates of Epithelial Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6475-8_12
Abstract: Cells are surrounded by mechanical stimuli in their microenvironment. It is important to determine how cells respond to the mechanical information that surrounds them in order to understand both development and disease progression, as well… read more here.
Keywords: epithelial cells; flow; culture model; culture ... See more keywords
A hybrid co-culture model with endothelial cells designed for the hepatic tissue engineering
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Materials Science: Materials in Medicine"
DOI: 10.1007/s10856-017-5950-3
Abstract: The cultured hepatic cells in vitro are prone to losing their characteristic morphologies and biological functions. To avoid this problem, a hybrid co-culture system was proposed to elucidate the effect of cellular communication on the… read more here.
Keywords: hybrid culture; hepatic cells; endothelial cells; culture model ... See more keywords
In vitro co-culture model of human monocyte-derived dendritic cells and T cells to evaluate the sensitization of dinitrochlorobenzene.
Sign Up to like & getrecommendations! Published in 2021 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2021.112331
Abstract: Exposure to sensitizer has been suggested to be hazardous to human health, evaluation the sensitization of sensitizer is particularly important and urgently needed. Dendritic cells (DCs) exert an irreplaceable function in immunity, and the T… read more here.
Keywords: dcs; model; dendritic cells; culture model ... See more keywords
A novel 3D culture model of fungal keratitis to explore host-pathogen interactions within the stromal environment.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental eye research"
DOI: 10.1016/j.exer.2021.108581
Abstract: Fungal keratitis (FK) pathology is driven by both fungal growth and inflammation within the corneal stroma. Standard in vitro infection models ̶ involving co-culture of the pathogen and the corneal cells in tissue culture medium… read more here.
Keywords: culture model; culture; host; fungal keratitis ... See more keywords
Immunomodulatory effects of polysaccharides enzymatic hydrolysis from Hericium erinaceus on the MODE-K/DCs co-culture model.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.07.131
Abstract: The aim of this study was to explore the indirect immunomodulatory activities and its mechanism of enzymatic hydrolysis of Hericium erinaceus polysaccharides (EHEP) in the MODE-K/DCs co-culture model. According to the TEER value, transmission of… read more here.
Keywords: mode; mode dcs; dcs culture; culture model ... See more keywords
Modelling early events in Mycobacterium bovis infection using a co-culture model of the bovine alveolus
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-75113-6
Abstract: Bovine tuberculosis (bTB), a zoonosis mainly caused by Mycobacterium bovis has severe socio-economic consequences and impact on animal health. Host–pathogen interactions during M. bovis infection are poorly understood, especially early events which are difficult to… read more here.
Keywords: bovis infection; mycobacterium bovis; infection; bovis ... See more keywords
Studies on the changes of uPA system in a co-culture model of bone marrow stromal cells–leukemia cells
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20194044
Abstract: Abstract The core of the tumor microenvironment in the hematological system is formed by bone marrow stromal cells (BMSCs). In the present study, we explored the interaction between the urokinase plasminogen activator (uPA) system and… read more here.
Keywords: system; bone marrow; culture model; upa system ... See more keywords
Advances in 3D cell culture for liver preclinical studies.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmab046
Abstract: The 3D cell culture model is an indispensable tool in the study of liver biology in the field of health and disease and the development of clinically relevant products for liver therapies. The 3D culture… read more here.
Keywords: preclinical studies; cell culture; advances cell; culture liver ... See more keywords
TMOD-26. ESTABLISHING A PATIENT-DERIVED, IN-VITRO ORGANOTYPIC SLICE CULTURE MODEL OF GBM
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.976
Abstract: Glioblastoma Multiforme (GBM) is the most common primary malignant brain tumour. This tumour is universally fatal with a median survival of 15 months. Driving this pathology is an extremely heterogeneic tumour and complex tumour microenvironment.… read more here.
Keywords: gbm; model gbm; model; culture model ... See more keywords
Modelling persistent Mycoplasma pneumoniae biofilm infections in a submerged BEAS-2B bronchial epithelial tissue culture model.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of medical microbiology"
DOI: 10.1099/jmm.0.001266
Abstract: Introduction. Infections with the respiratory pathogen Mycoplasma pneumoniae are often chronic, recurrent and resistant, persisting after antibiotic treatment. M. pneumoniae grown on glass forms protective biofilms, consistent with a role for biofilms in persistence. These… read more here.
Keywords: microscopy; tissue culture; pneumoniae; model ... See more keywords