An Automatable Hydrogel Culture Platform for Evaluating Efficacy of Antibody-based Therapeutics in Overcoming Chemoresistance.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology journal"
DOI: 10.1002/biot.201900439
Abstract: The microenvironment plays a major role in conferring chemoresistance to cancer cells. In order to better inform clinical response to chemoresistance, preclinical models that recapitulate its hallmark features are needed to enable screening for resistance-specific… read more here.
Keywords: chemoresistance; efficacy; culture platform; platform ... See more keywords
A flexible microbial co-culture platform for simultaneous utilization of methane and carbon dioxide from gas feedstocks.
Sign Up to like & getrecommendations! Published in 2017 at "Bioresource technology"
DOI: 10.1016/j.biortech.2016.12.111
Abstract: A new co-cultivation technology is presented that converts greenhouse gasses, CH4 and CO2, into microbial biomass. The methanotrophic bacterium, Methylomicrobium alcaliphilum 20z, was coupled to a cyanobacterium, Synechococcus PCC 7002 via oxygenic photosynthesis. The system… read more here.
Keywords: platform simultaneous; flexible microbial; microbial culture; gas ... See more keywords
Abstract 2051: Perfusable 3D angiogenesis in a high-throughput microfluidic culture platform
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-2051
Abstract: The transition from 2D to 3D cell culture is a first step towards more physiologically relevant in vitro cancer models. To adequately capture the complex tissue architectures observed in vivo, 3D microfluidic techniques incorporate and… read more here.
Keywords: angiogenesis; platform; culture platform; cancer ... See more keywords
Abstract 4563: Measuring immunotherapy responses ex vivo using novel 3D culture platform: E-slice
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4563
Abstract: Immunotherapies have provided dramatic and life-saving results in some patients; however, their effectiveness varies greatly in different tumors, even among patients with the same clinical diagnosis. Clearly, a better system to evaluate the personalized response… read more here.
Keywords: platform; culture platform; immunotherapy responses; slice ... See more keywords
A Microcavity Array-Based 4D Cell Culture Platform
Sign Up to like & getrecommendations! Published in 2019 at "Bioengineering"
DOI: 10.3390/bioengineering6020050
Abstract: (1) Background: We describe a 4D cell culture platform with which we tried to detect and to characterize migration dynamics of single hematopoietic stem cells in polymer film microcavity arrays integrated into a microtiter plate.… read more here.
Keywords: culture platform; cell culture; cell; hematopoietic stem ... See more keywords