Detection of Protein Uptake in In Vitro Cultured Astrocytes Exemplified by the Uptake of the Serine Protease, Tissue Plasminogen Activator.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9068-9_14
Abstract: Astrocytes are heterogeneous cells of the central nervous system whose uptake of neurotransmitters and neuromodulators can influence synaptic signaling. Any malfunction in this process can lead to serious defects in synaptic transmission found in, for… read more here.
Keywords: serine protease; cultured astrocytes; vitro cultured; plasminogen activator ... See more keywords
Bidirectional modulation of TNF-α transcription via α- and β-adrenoceptors in cultured astrocytes from rat spinal cord.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.05.011
Abstract: Noradrenaline (NA) suppresses TNF-α production via β-adrenoceptors (ARs) in brain astrocytes. However, the downstream pathways from β-ARs, and the involvement of α-ARs, remains unknown. In this study, we investigated the AR-mediated regulation of TNF-α mRNA… read more here.
Keywords: astrocytes rat; tnf; via adrenoceptors; cultured astrocytes ... See more keywords
Identification of the expression of farnesoid X receptor in astrocytes
Sign Up to like & getrecommendations! Published in 2021 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001717
Abstract: Recently, we have identified a functional expression of farnesoid X receptor (FXR) in neurons in vitro and in vivo. However, whether the FXR is expressed in astrocytes remains unclear. In the present study, we addressed… read more here.
Keywords: expression; expression farnesoid; farnesoid receptor; cultured astrocytes ... See more keywords
Validation of a System xc– Functional Assay in Cultured Astrocytes and Nervous Tissue Samples
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.815771
Abstract: Disruption of the glutamatergic homeostasis is commonly observed in neurological diseases and has been frequently correlated with the altered expression and/or function of astrocytic high-affinity glutamate transporters. There is, however, a growing interest for the… read more here.
Keywords: system; glutamate; cultured astrocytes; tissue samples ... See more keywords
Inhibition of angiotensin converting enzyme increases PKCβI isoform expression via activation of substance P and bradykinin receptors in cultured astrocytes of mice
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Veterinary Science"
DOI: 10.4142/jvs.22275
Abstract: Background Angiotensin-converting enzyme inhibitor (ACEi) inhibits the catalysis of angiotensin I to angiotensin II and the degradation of substance P (SP) and bradykinin (BK). While the possible relationship between ACEi and SP in nociceptive mice… read more here.
Keywords: converting enzyme; cultured astrocytes; expression; pkc isoform ... See more keywords