Extending the viability of human precision-cut intestinal slice model for drug metabolism studies.
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DOI: 10.1007/s00204-022-03295-1
Abstract: Human Precision-cut intestinal slices (hPCIS) are used to study intestinal physiology, pathophysiology, drug efficacy, toxicology, kinetics, and metabolism. However, the use of this ex vivo model is restricted to approximately a 24 h timeframe because of… read more here.
Keywords: toxicology; metabolism; viability; cultured hpcis ... See more keywords