Alterations of cultured myotubes and fasting plasma metabolite profiles related to mitochondrial dysfunction in Type 2 diabetes subjects
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.04.104
Abstract: A plethora of metabolic profiling studies have identified several metabolic signatures in the patient’s biofluids and tissues to be correlated with type 2 diabetes (T2D) and its comorbidities. However, the association between specific metabolite-based markers… read more here.
Keywords: myotubes fasting; plasma; type diabetes; mitochondrial dysfunction ... See more keywords
Efficient and modified 2-NBDG assay to measure glucose uptake in cultured myotubes.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pharmacological and toxicological methods"
DOI: 10.1016/j.vascn.2021.107069
Abstract: Under type-2 diabetes, insulin resistance develops in skeletal muscles as a key defect and to study the disorder, its manifestation, and possible solution, measurement of glucose uptake is a fundamental necessity. Of various approaches (i.e.… read more here.
Keywords: efficient modified; assay measure; glucose uptake; nbdg assay ... See more keywords