Simvastatin Inhibits CYR61 Expression in Orbital Fibroblasts in Graves' Ophthalmopathy through the Regulation of FoxO3a Signaling
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DOI: 10.1155/2021/8888913
Abstract: Graves' ophthalmopathy (GO), which is characterized by orbital tissue inflammation, expansion, and fibrosis, is the ocular manifestation in 25% to 50% of patients with Graves' disease. As the pathology of GO is driven by autoimmune… read more here.
Keywords: graves ophthalmopathy; orbital fibroblasts; cyr61 expression; cultured orbital ... See more keywords