Activation of urotensin II receptor induces podocyte injury via TRPC6-mediated endoplasmic reticulum stress
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5731204
Abstract: Podocytes are essential for the glomerular filtration barrier in the kidney. Podocyte injury can lead to chronic kidney disease (CKD). One of the leading causes of CKD is diabetes mellitus. Plasma urotensin II (UII) levels… read more here.
Keywords: stress; cultured podocytes; trpc6; podocyte injury ... See more keywords
Knockout of the neonatal Fc receptor alters immune complex trafficking and lysosomal function in cultured podocytes.
Sign Up to like & getrecommendations! Published in 2023 at "PloS one"
DOI: 10.1371/journal.pone.0284636
Abstract: Podocytes are key to preventing the filtration of serum proteins into the urine. Recent evidence also suggests that in immune mediated kidney diseases, podocytes are the targets of immune complexes (ICs). The mechanisms whereby podocytes… read more here.
Keywords: neonatal receptor; cultured podocytes; knockout neonatal; alters immune ... See more keywords