Identification of cCMP and cUMP Substrate Proteins and Cross Talk Between cNMPs.
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DOI: 10.1007/164_2015_38
Abstract: cCMP and cUMP are pyrimidine cyclic nucleotides which are present in several types of cells. These molecules could exert diverse cellular functions and might act as second messengers. In the last years, diverse approaches were… read more here.
Keywords: identification ccmp; cross talk; cump substrate; cump ... See more keywords
Inactivation of Non-canonical Cyclic Nucleotides: Hydrolysis and Transport.
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DOI: 10.1007/164_2016_5004
Abstract: This chapter addresses cNMP hydrolysis by phosphodiesterases (PDEs) and export by multidrug resistance associated proteins (MRPs). Both mechanisms are well-established for the canonical cNMPs, cAMP, and cGMP. Increasing evidence shows that non-canonical cNMPs (specifically cCMP,… read more here.
Keywords: canonical cnmps; canonical cyclic; non canonical; hydrolysis ... See more keywords
cUMP elicits interendothelial gap formation during Pseudomonas aeruginosa infection
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Physiology - Lung Cellular and Molecular Physiology"
DOI: 10.1152/ajplung.00164.2023
Abstract: P. aeruginosa utilizes a type 3 secretion system to intoxicate host cells with the nucleotidyl cyclase ExoY. After activation by its host cell cofactor, filamentous actin, ExoY produces purine and pyrimidine cyclic nucleotides, including cAMP,… read more here.
Keywords: aeruginosa infection; physiology; gap formation; cump ... See more keywords