Fibroblast growth factor 10 markedly improves in vitro maturation of porcine cumulus‐oocyte complexes
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22756
Abstract: Growth factors synthesized by ovarian somatic cells affect cumulus cell expansion and oocyte maturation in vitro. Fibroblast growth factor 10 (FGF10), for example, is a known regulator of mammalian cumulus‐oocyte complex maturation. In this study,… read more here.
Keywords: cell; cumulus; oocyte; treated group ... See more keywords
Transporting cumulus complexes using novel meiotic arresting conditions permits maintenance of oocyte developmental competence
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-017-0958-7
Abstract: PurposeThe aim of this study is to evaluate the effect of a novel bovine cumulus oocyte complex (COC) shipping media designed to arrest meiotic resumption during transport on meiotic arrest, as well as meiotic resumption,… read more here.
Keywords: oocyte developmental; cumulus; control; developmental competence ... See more keywords
Supplementing in vitro embryo production media by NPPC and sildenafil affect the cytoplasmic lipid content and gene expression of bovine cumulus-oocyte complexes and embryos.
Sign Up to like & getrecommendations! Published in 2018 at "Reproductive biology"
DOI: 10.1016/j.repbio.2018.01.004
Abstract: In our study, we added natriuretic peptide type C (NPPC) and/or sildenafil during in vitro maturation (IVM) of bovine cumulus-oocyte complexes (COCs) followed by in vitro culture (IVC) of embryos with or without sildenafil. We… read more here.
Keywords: cumulus; cumulus oocyte; embryo; nppc sildenafil ... See more keywords
Cumulus-oocyte interactions and programmed cell death in bovine embryos produced in vitro.
Sign Up to like & getrecommendations! Published in 2019 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2018.11.028
Abstract: This study investigated the interactions between cumulus cells (CCs) and oocytes and programmed cell death in bovine cumulus-oocyte complexes (COCs) with different morphological characteristics. DNA fragmentation was assessed in CCs at 0 and 24 h of… read more here.
Keywords: cumulus; cumulus oocyte; programmed cell; cell death ... See more keywords
Cumulus cell-derived and maternal SIRT6 differentially regulates porcine oocyte meiotic maturation.
Sign Up to like & getrecommendations! Published in 2019 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2019.09.048
Abstract: SIRT6, a member of the sirtuin family, is a NAD + dependent protein deacetylase and has been implicated in transcriptional regulation of somatic cells and post-transcriptional regulation of oocyte meiosis. However, the function of cumulus cell-derived and… read more here.
Keywords: cumulus; maternal sirt6; meiotic maturation; cumulus cell ... See more keywords
Understanding Negative Subtropical Shallow Cumulus Cloud Feedbacks in a Near‐Global Aquaplanet Model Using Limited Area Cloud‐Resolving Simulations
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Advances in Modeling Earth Systems"
DOI: 10.1029/2018ms001572
Abstract: Limited area cloud‐resolving model (CRM) simulations called LASAM are used to reproduce and understand negative subtropical shallow cumulus cloud feedbacks in a near‐global aquaplanet CRM (NGAqua) with 4‐K sea surface temperature (SST) warming. NGAqua spans… read more here.
Keywords: area; cumulus; cloud; radiative cooling ... See more keywords
The follicle-stimulating hormone triggers rapid changes in mitochondrial structure and function in porcine cumulus cells
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-023-50586-3
Abstract: Oocyte maturation is a key process during which the female germ cell undergoes resumption of meiosis and completes its preparation for embryonic development including cytoplasmic and epigenetic maturation. The cumulus cells directly surrounding the oocyte… read more here.
Keywords: function porcine; stimulating hormone; porcine cumulus; cumulus ... See more keywords
Single-cell RNA-seq reveals the effects of the FecB mutation on the transcriptome profile in ovine cumulus cells
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DOI: 10.1038/s41598-024-64001-y
Abstract: Genetic variations in the ovine ovulation rate, which are associated with the FecB mutation, provide useful models by which to explore the mechanisms regulating the development of mammalian antral follicles. In order to study the… read more here.
Keywords: cumulus; cell; fecb mutation; cumulus cells ... See more keywords
Non-muscle myosin II-dependent cumulus cell migration at ovulation is required for sperm to reach the egg in mice
Sign Up to like & getrecommendations! Published in 2025 at "Communications Biology"
DOI: 10.1038/s42003-025-08736-y
Abstract: At ovulation in mammals, epidermal growth factor (EGFR) signaling in the cumulus granulosa cells that enclose the egg causes them to generate an extracellular matrix and become dispersed within it. This process, termed expansion, is… read more here.
Keywords: egg; muscle myosin; cumulus; non muscle ... See more keywords
161 Cumulus Cell Luteinization is Enhanced During Aging of Bovine Oocytes Matured In Vitro
Sign Up to like & getrecommendations! Published in 2018 at "Reproduction, Fertility and Development"
DOI: 10.1071/rdv30n1ab161
Abstract: Maturing mammalian oocytes can prevent luteinization of cumulus cells (CC) both in vivo and in vitro by regulating CC steroidogenesis (Gilchrist et al. 2004 Anim. Reprod. Sci. 82-83, 431-446; Ramirez et al. 2016 Anim. Reprod.… read more here.
Keywords: cumulus; bovine; expression; aging bovine ... See more keywords
Suppression of oocyte glycine transporter activity in mouse cumulus-oocyte complexes before resumption of meiosis†.
Sign Up to like & getrecommendations! Published in 2025 at "Biology of reproduction"
DOI: 10.1093/biolre/ioaf080
Abstract: Glycine is a key regulator of cell volume in early preimplantation mouse embryos and supports embryo viability. Its accumulation is initiated when the GLYT1 glycine transporter (SLC6A9) is activated in oocytes at about the same… read more here.
Keywords: arrest; cumulus; oocyte; glycine transporter ... See more keywords