Cuplike nuclear morphology in pediatric B-cell acute lymphoblastic leukemia.
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DOI: 10.1182/blood-2018-05-848788
Abstract: ![Figure][1] A 7-year-old previously healthy girl presented with fever, fatigue, and weight loss for 1 month. Laboratory test revealed normocytic anemia (hemoglobin, 7.1 g/dL), neutropenia (0.17 × 109/L), and 30% small- to medium-sized blasts with… read more here.
Keywords: cell acute; cuplike nuclear; cuplike; morphology pediatric ... See more keywords
Cuplike nuclear morphology is highly associated with IKZF1 deletion in pediatric precursor B-cell ALL.
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DOI: 10.1182/blood.2019000604
Abstract: TO THE EDITOR: Cuplike nuclei (CLN) (nuclei with prominent invagination) are recognized as a distinctive morphologic finding in the blasts of acute myeloid leukemia (AML).[1][1][⇓][2][⇓][3][⇓][4][⇓][5]-[6][6] They are seen in ∼20% of all AML cases[2][2],[4][4],[5][5] and… read more here.
Keywords: highly associated; associated ikzf1; cuplike nuclear; ikzf1 deletion ... See more keywords