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Published in 2017 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-017-0936-0
Abstract: BackgroundMultiple sclerosis (MS) is an inflammatory demyelinating disease classically associated with axonal damage and loss; more recently, however, synaptic changes have been recognized as additional contributing factors. An anatomical area commonly affected in MS is…
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Keywords:
demyelination;
synaptic changes;
cuprizone model;
inflammatory demyelination ... See more keywords
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Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232416093
Abstract: Remyelination therapies, which are currently under development, have a great potential to delay, prevent or even reverse disability in multiple sclerosis patients. Several models are available to study the effectiveness of novel compounds in vivo,…
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Keywords:
cuprizone model;
remyelination;
remyelination multiple;
model ... See more keywords