Articles with "cuprizone model" as a keyword



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Inflammatory demyelination alters subcortical visual circuits

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Published in 2017 at "Journal of Neuroinflammation"

DOI: 10.1186/s12974-017-0936-0

Abstract: BackgroundMultiple sclerosis (MS) is an inflammatory demyelinating disease classically associated with axonal damage and loss; more recently, however, synaptic changes have been recognized as additional contributing factors. An anatomical area commonly affected in MS is… read more here.

Keywords: demyelination; synaptic changes; cuprizone model; inflammatory demyelination ... See more keywords
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Remyelination in Multiple Sclerosis: Findings in the Cuprizone Model

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232416093

Abstract: Remyelination therapies, which are currently under development, have a great potential to delay, prevent or even reverse disability in multiple sclerosis patients. Several models are available to study the effectiveness of novel compounds in vivo,… read more here.

Keywords: cuprizone model; remyelination; remyelination multiple; model ... See more keywords