Cuproptosis Induced by ROS Responsive Nanoparticles with Elesclomol and Copper Combined with αPD‐L1 for Enhanced Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials"
DOI: 10.1002/adma.202212267
Abstract: Cuproptosis is a new cell death that depends on copper (Cu) ionophores to transport Cu into cancer cells, which induces cell death. However, existing Cu ionophores are small molecules with a short blood half‐life making… read more here.
Keywords: cell death; cuproptosis; cancer; copper ... See more keywords
Construction of a cuproptosis‐related lncRNA signature for predicting prognosis and immune landscape in osteosarcoma patients
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5214
Abstract: Long noncoding RNAs (lncRNAs) influence the onset of osteosarcoma. Cuproptosis is a novel cell death mechanism. We attempted to identify a cuproptosis‐related lncRNA signature to predict the prognosis and immune landscape in osteosarcoma patients. read more here.
Keywords: related lncrna; cuproptosis; lncrna signature; immune landscape ... See more keywords
Identification of cuproptosis‐related subtypes and characterization of the tumor microenvironment landscape in head and neck squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24638
Abstract: Cuproptosis is considered a novel copper‐dependent cell death model. In this study, we established a novel scoring system based on 10 cuproptosis‐related genes (CRGs) to predict the prognosis and immune landscape of head and neck… read more here.
Keywords: landscape head; cuproptosis; cell; head neck ... See more keywords
Cuproptosis-Mediated Patterns Characterized by Distinct Tumor Microenvironment and Predicted the Immunotherapy Response for Gastric Cancer
Sign Up to like & getrecommendations! Published in 2023 at "ACS Omega"
DOI: 10.1021/acsomega.2c07052
Abstract: Cuproptosis is a newly discovered programmed cell death process, and several cuproptosis-related genes have been reported to regulate cancer cell proliferation and progression. The association between cuproptosis and tumor microenvironment in gastric cancer (GC) remains… read more here.
Keywords: immunotherapy response; cuproptosis; cancer; tumor microenvironment ... See more keywords
Cuproptosis-related gene signatures for predicting prognosis of lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030446
Abstract: Lung cancer (LC) is a common malignancy with high mortality rate, and lung adenocarcinoma (LUAD) is one of the common pathological types. Cuproptosis is a recently discovered new type of cell death dependent on mitochondria.… read more here.
Keywords: cuproptosis; prognosis; lung adenocarcinoma; risk ... See more keywords
A novel prognostic signature for lung adenocarcinoma based on cuproptosis-related lncRNAs: A Review
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000031924
Abstract: Lung adenocarcinoma (LUAD) is a highly heterogeneous disease with complex pathogenesis, high mortality, and poor prognosis. Cuproptosis is a new type of programmed cell death triggered by copper accumulation that may play an important role… read more here.
Keywords: cuproptosis; prognostic signature; novel prognostic; analysis ... See more keywords
Cuproptosis-associated genes and immune microenvironment characterization in breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032301
Abstract: Excess Cu can cause cell death as a cofactor for essential enzymes. The relationship between cuproptosis-associated genes (CAGs) and breast cancer (BR) is not completely investigated. Here, the transcriptome expression and mutation profile data of… read more here.
Keywords: cuproptosis associated; cuproptosis; risk; cancer ... See more keywords
Comprehensive analyses of cuproptosis-related gene CDKN2A on prognosis and immunologic therapy in human tumors
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000033468
Abstract: Recent studies have identified a novel programmed cell death based on copper, named cuproptosis. However, as an anti-cuproptosis gene, the functional roles, definite mechanisms and prognostic value of CDKN2A in pan-cancer are largely unclear. The… read more here.
Keywords: cuproptosis; cdkn2a; expression; analysis ... See more keywords
Identification of cuproptosis‐related lncRNAs for prognosis and immunotherapy in glioma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.17603
Abstract: Glioma is a highly invasive primary brain tumour, making it challenging to accurately predict prognosis for glioma patients. Cuproptosis is a recently discovered cell death attracting significant attention in the tumour field. Whether cuproptosis‐related genes… read more here.
Keywords: cuproptosis; high risk; related lncrnas; risk ... See more keywords
Definition of a Novel Cuproptosis-Relevant lncRNA Signature for Uncovering Distinct Survival, Genomic Alterations, and Treatment Implications in Lung Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/2756611
Abstract: Objective Cuproptosis is a newly discovered copper-independent cell death modality, and limited evidence suggests the critical implications in human cancers. Nonetheless, the clinical impacts of cuproptosis-relevant lncRNAs in lung adenocarcinoma (LUAD) remain largely ill-defined. The… read more here.
Keywords: cuproptosis; relevant lncrna; genomic alterations; cuproptosis relevant ... See more keywords
Cuproptosis-Related Signature Predicts the Prognosis, Tumor Microenvironment, and Drug Sensitivity of Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/3393027
Abstract: Background Copper (Cu) metabolism is strongly associated with liver disease. Cuproptosis is a novel format of cell death, and cuproptosis-related genes (CRGs) were identified. However, the role of CRGs in Hepatocellular Carcinoma (HCC) remains unknown.… read more here.
Keywords: cuproptosis; signature; hcc; analysis ... See more keywords