Cuproptosis-associated genes and immune microenvironment characterization in breast cancer
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DOI: 10.1097/md.0000000000032301
Abstract: Excess Cu can cause cell death as a cofactor for essential enzymes. The relationship between cuproptosis-associated genes (CAGs) and breast cancer (BR) is not completely investigated. Here, the transcriptome expression and mutation profile data of… read more here.
Keywords: cuproptosis associated; cuproptosis; risk; cancer ... See more keywords
Construction of a cuproptosis-associated long non-coding RNA risk prediction model for pancreatic adenocarcinoma based on the TCGA database
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DOI: 10.1097/md.0000000000032808
Abstract: Cuproptosis is a recently identified controlled process of cell death that functions in tumor development and treatment. Long non-coding RNAs (lncRNAs) are RNA molecules longer than 200 nucleotides that bind to transcription factors and regulate… read more here.
Keywords: cuproptosis associated; pancreatic adenocarcinoma; risk; prediction model ... See more keywords
Cuproptosis-associated lncRNAs discern prognosis and immune microenvironment in sarcoma victims
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DOI: 10.3389/fcell.2022.989882
Abstract: Cuproptosis is a fresh form of the copper-elesclomol-triggered, mitochondrial tricarboxylic acid (TCA) dependent cell death. Yet, the subsumed mechanism of cuproptosis-associated lncRNAs in carcinoma is not wholly clarified. Here, We appraised 580 cuproptosis-associated lncRNAs in… read more here.
Keywords: cuproptosis associated; cuproptosis; sarcoma; immune microenvironment ... See more keywords
Cuproptosis-Associated lncRNA Establishes New Prognostic Profile and Predicts Immunotherapy Response in Clear Cell Renal Cell Carcinoma
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DOI: 10.3389/fgene.2022.938259
Abstract: Background: Clear cell renal cell carcinoma (ccRCC) accounts for 80% of all kidney cancers and has a poor prognosis. Recent studies have shown that copper-dependent, regulated cell death differs from previously known death mechanisms (apoptosis,… read more here.
Keywords: cuproptosis associated; cell; cuproptosis; ccrcc ... See more keywords
A comprehensive analysis and validation of cuproptosis-associated genes across cancers: Overall survival, the tumor microenvironment, stemness scores, and drug sensitivity
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DOI: 10.3389/fgene.2022.939956
Abstract: Background: Cuproptosis is a novel type of cell death induced by copper. Cuproptosis-associated genes play a crucial part in oncogenesis and the growth and metastasis of tumors. However, the correlations among cuproptosis-associated genes, overall survival,… read more here.
Keywords: cuproptosis associated; cuproptosis; tumor microenvironment; associated genes ... See more keywords
Comprehensive analysis of the cuproptosis-related model to predict prognosis and indicate tumor immune infiltration in lung adenocarcinoma
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DOI: 10.3389/fonc.2022.935672
Abstract: Background Cuproptosis is a novel form of programmed cell death termed as Cu-dependent cytotoxicity. However, the roles of cuproptosis-associated genes (CAGs) in lung adenocarcinoma (LUAD) have not been explored comprehensively. Methods We obtained CAGs and… read more here.
Keywords: infiltration; cuproptosis associated; cuproptosis; luad patients ... See more keywords
Development and validation of cuproptosis-associated prognostic signatures in WHO 2/3 glioma
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DOI: 10.3389/fonc.2022.967159
Abstract: WHO 2/3 glioma is a common intracranial tumor that seriously affects the quality of life and survival time of patients. Previous studies have shown that the tricarboxylic acid (TCA) cycle is closely related to the… read more here.
Keywords: cuproptosis associated; cuproptosis; closely related; development ... See more keywords