Articles with "cuprotosis" as a keyword



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Construction of a Cuprotosis-Related Gene-Based Model to Improve the Prognostic Evaluation of Patients with Gastric Cancer

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Published in 2022 at "Journal of Immunology Research"

DOI: 10.1155/2022/8087622

Abstract: Background Gastric cancer (GC) is one of the most serious gastrointestinal malignancies with bad prognosis. The association between GC and cuprotosis-related genes has not been reported. Methods The clinical and RNA expression of patients with… read more here.

Keywords: cuprotosis; cuprotosis related; gastric cancer; model ... See more keywords
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Cuprotosis Patterns Are Associated with Tumor Mutation Burden and Immune Landscape in Lung Adenocarcinoma

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Published in 2022 at "Journal of Oncology"

DOI: 10.1155/2022/9772208

Abstract: Background The association involving cuprotosis, molecular subtype, and specific immune cell groups in the tumor microenvironment has been focused on by more recent studies. In lung adenocarcinoma (LUAD), the potential functions of cuprotosis remain elusive.… read more here.

Keywords: cuprotosis; luad; cuprotosis patterns; immune landscape ... See more keywords
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Construction and Validation of a risk model Based on Cuprotosis-related LncRNAsin Colon Adenocarcinoma.

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Published in 2022 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2022.68.12.16

Abstract: Cancer cells are significantly impacted by copper-induced cell death (cuprotosis). Long noncoding RNAs (lncRNAs) are crucial in the developmental process of colon adenocarcinoma  (COAD). The ability of Cuprotosis-related lncRNA biomarkers to predict COAD prognosis, on… read more here.

Keywords: cuprotosis; cuprotosis related; colon adenocarcinoma; model risk ... See more keywords
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Cuprotosis-related signature predicts overall survival in clear cell renal cell carcinoma

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.922995

Abstract: Background: Cuprotosis is a new form of programmed cell death induced by copper. We explored the correlation of cuprotosis with clear cell renal cell carcinoma (ccRCC) and constructed a cuprotosis-related signature to predict the prognosis… read more here.

Keywords: cuprotosis; cell; cuprotosis related; related signature ... See more keywords
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Machine learning-based characterization of cuprotosis-related biomarkers and immune infiltration in Parkinson’s disease

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Published in 2022 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2022.1010361

Abstract: Background: Parkinson’s disease (PD) is a neurodegenerative disease commonly seen in the elderly. On the other hand, cuprotosis is a new copper-dependent type of cell death that can be observed in various diseases. Methods: This… read more here.

Keywords: infiltration; cuprotosis; cuprotosis related; disease ... See more keywords
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Identification of core cuprotosis-correlated biomarkers in abdominal aortic aneurysm immune microenvironment based on bioinformatics

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1138126

Abstract: Background The occurrence of abdominal aortic aneurysms (AAAs) is related to the disorder of immune microenvironment. Cuprotosis was reported to influence the immune microenvironment. The objective of this study is to identify cuprotosis-related genes involved… read more here.

Keywords: cuprotosis; cuprotosis related; immune microenvironment; abdominal aortic ... See more keywords
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Integrative analysis revealed that distinct cuprotosis patterns reshaped tumor microenvironment and responses to immunotherapy of colorectal cancer

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1165101

Abstract: Background Cuprotosis is a novel form of programmed cell death that involves direct targeting of key enzymes in the tricarboxylic acid (TCA) cycle by excess copper and may result in mitochondrial metabolic dysfunction. However, whether… read more here.

Keywords: cuprotosis; cuprotosis patterns; tumor microenvironment; analysis ... See more keywords