Curcumin suppresses gastric cancer by inhibiting gastrin‐mediated acid secretion
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12237
Abstract: Hyperacidity in the stomach is known to promote the progression of gastric cancer. The plant‐derived chemotherapeutic curcumin is used to treat gastric cancer. The objective of this study was to investigate whether curcumin regulates gastrin‐mediated… read more here.
Keywords: mediated acid; secretion; gastric cancer; gastrin mediated ... See more keywords
Conjugation of micro/nanocurcumin particles to ZnO nanoparticles changes the surface charge and hydrodynamic size thereby enhancing its antibacterial activity against Escherichia coli and Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1968
Abstract: Nanobiotechnology‐mediated synthesis of ZnO nanoparticles, micro/nanocurcumin, and curcumin–ZnO nanocomposites and their characterization followed by comparative study of their antibacterial, antioxidant, and iron‐chelating efficiency at various dosages are discussed. Micro/nanocurcumin and ZnO nanoparticles were synthesized using… read more here.
Keywords: micro nanocurcumin; zno; spectroscopy; zno nanoparticles ... See more keywords
Curcumin inhibits colon cancer malignant progression and promotes T cell killing by regulating miR-206 expression.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical anatomy"
DOI: 10.1002/ca.24057
Abstract: Colon cancer is a great threat to human health. Curcumin, as a traditional Chinese medicine extract with anti-tumor and anti-inflammatory effects, can affect the development of diverse human diseases including cancer. The aim of this… read more here.
Keywords: curcumin; expression; mir 206; colon cancer ... See more keywords
Polypyridyl CoII‐Curcumin Complexes as Photoactivated Anticancer and Antibacterial Agents
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DOI: 10.1002/cbic.202300033
Abstract: Four new CoII complexes, [Co(bpy)2(acac)]Cl (1), [Co(phen)2(acac)]Cl (2), [Co(bpy)2(cur)]Cl (3), [Co(phen)2(cur)]Cl (4), where bpy=2,2’‐bipyridine (1 and 3), phen=1,10‐phenanthroline (2 and 4), acac=acetylacetonate (1 and 2), cur=curcumin monoanion (3 and 4) have been designed, synthesized and… read more here.
Keywords: polypyridyl coii; curcumin complexes; curcumin; coii curcumin ... See more keywords
Curcumin attenuates isoniazid‐induced hepatotoxicity by upregulating the SIRT1/PGC‐1α/NRF1 pathway
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4288
Abstract: As a serious infectious disease, tuberculosis threatens global public health. Isoniazid is the first‐line drug not only in active tuberculosis but also in its prevention. Severe hepatotoxicity greatly limits its use. Curcumin, extracted from turmeric,… read more here.
Keywords: sirt1 pgc; isoniazid induced; curcumin; hepatotoxicity ... See more keywords
Impact of solid lipid nanoparticles on 3T3 fibroblasts viability and lipid profile: The effect of curcumin and resveratrol loading
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4379
Abstract: This study focused on the impact in 3T3 fibroblasts of several types of empty and curcumin‐ and resveratrol‐loaded solid lipid nanoparticles (SLN) on cell viability and lipid metabolism in relation to their lipid content and… read more here.
Keywords: resveratrol; solid lipid; 3t3 fibroblasts; curcumin ... See more keywords
Safety assessment of a solid lipid curcumin particle preparation: In vitro and in vivo genotoxicity studies
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4434
Abstract: Curcumin, one of the three principal curcuminoids found within turmeric rhizomes, has long been associated with numerous physiologically beneficial effects; however, its efficacy is limited by its inherently low bioavailability. Several novel formulations of curcumin… read more here.
Keywords: particle preparation; solid lipid; curcumin; curcumin particle ... See more keywords
Curcumin suppressed the prostate cancer by inhibiting JNK pathways via epigenetic regulation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22049
Abstract: Curcumin is a component of turmeric and is isolated from the rhizomes of the plant Curcuma longa. Curcumin was reported to have therapeutic effects on prostate cancer. Yet the molecular mechanism of curcumin remains unclear.… read more here.
Keywords: epigenetic regulation; prostate cancer; curcumin;
Curcumin induced apoptosis is mediated through oxidative stress in mutated p53 and wild type p53 colon adenocarcinoma cell lines
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22616
Abstract: Curcumin has anti‐oxidant, anti‐cancer and anti‐carcinogen property. Our laboratory had previously reported that, curcumin treatment induces reactive oxygen species (ROS) generation in HT‐29 cell line, an effect contradictory to its anti‐oxidant property. This study evaluates… read more here.
Keywords: hct 116; cell lines; curcumin induced; p53 ... See more keywords
Unraveling the biomechanistic role of Rac1/TWEAK/Fn14/NF‐κB intricate network in experimentally doxorubicin‐induced cardiotoxicity in rats: The role of curcumin
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22829
Abstract: Doxorubicin (DOX) is an important chemotherapeutic drug. Cardiotoxicity diminishes its clinical efficacy. We aimed to focus on the mechanism of DOX‐induced cardiotoxicity, in addition, to evaluate curcumin's protective effect against it. Twenty‐eight rats were divided… read more here.
Keywords: induced cardiotoxicity; group; cardiotoxicity; role ... See more keywords
Gliadin induced oxidative stress and altered cellular responses in human intestinal cells: An in‐vitro study to understand the cross‐talk between the transcription factor Nrf‐2 and multifunctional APE1 enzyme
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23096
Abstract: The present study examined the wheat protein gliadin‐induced oxidative and nitrosative stress and its downstream responses in human intestinal HCT‐116 and HT‐29 cells. The beneficial role of dietary phytochemical curcumin and role of multifunctional enzyme… read more here.
Keywords: stress; curcumin; induced oxidative; gliadin ... See more keywords