Curcumin activates G protein-coupled receptor 97 (GPR97) in a manner different from glucocorticoid.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2022.01.075
Abstract: Curcumin is a yellow pigment in turmeric (Curcuma longa) with various physiological effects in the body. To elucidate the molecular mechanisms by which bioactive compounds exert their function, identification of their molecular targets is crucial.… read more here.
Keywords: response; gpr97; glucocorticoid; receptor ... See more keywords
Curcumin Activates Vagal Afferent Neurons Through the Modulation of Ion Channels via α7 nAChR
Sign Up to like & getrecommendations! Published in 2019 at "Natural Product Communications"
DOI: 10.1177/1934578x19873738
Abstract: Curcumin, a plant polyphenol, has been previously reported to attenuate collagen-induced arthritis in rats by modulating the function of the cholinergic system, but the underlying mechanism remains to be identified. In this study, primary nodose… read more here.
Keywords: afferent neurons; activates vagal; curcumin; neurons modulation ... See more keywords
Curcumin activates the Nrf2 pathway and induces cellular protection against oxidative injury.
Sign Up to like & getrecommendations! Published in 2019 at "Current molecular medicine"
DOI: 10.2174/1566524019666191016150757
Abstract: Curcumin is a naturally occurring polyphenol which is isolated from the rhizome of Curcuma longa (turmeric). This medicinal compound has different biological activities including antioxidant, antibacterial, antineoplastic, and anti-inflammation. It has also therapeutic effects for… read more here.
Keywords: pathway induces; nrf2 pathway; curcumin activates; pathway ... See more keywords