Antioxidant and anti‐inflammatory effects of the monocarbonyl curcumin analogs B2BRBC and C66 in monocrotaline‐induced right ventricular hypertrophy
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22353
Abstract: For 22 days after monocrotaline injection two groups of rats received either of the monocarbonyl curcumin analogs (2E,6E)‐2,6‐bis(2‐bromobenzylidene)cycloxehanone (B2BrBC) and (2E,6E)‐2,6‐bis([2‐trifluoromethyl]benzylidene)cyclohexanone (C66), and their right ventricle parameters were compared to those from the control and… read more here.
Keywords: monocrotaline; curcumin analogs; b2brbc c66; monocarbonyl curcumin ... See more keywords
Curcumin analogs: synthesis and biological activities
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DOI: 10.1007/s00044-019-02497-0
Abstract: Curcumin has received great attention in the past three decades due to its versatile medicinal activities, which are attributed to the presence of certain functional groups in its structure. Despite this, the application of curcumin… read more here.
Keywords: synthesized analogs; synthesis biological; curcumin; activity ... See more keywords
Novel curcumin analogs act as antagonists to control nosocomial infection causing Pseudomonas aeruginosa
Sign Up to like & getrecommendations! Published in 2019 at "Biocatalysis and Agricultural Biotechnology"
DOI: 10.1016/j.bcab.2019.101238
Abstract: Abstract Pseudomonas aeruginosa has become the important cause of hospital acquired nosocomial infection which is one of the leading cause of death in today's world. Here, we synthesized structurally similar analogs of curcumin (G0-G4) as… read more here.
Keywords: curcumin analogs; novel curcumin; pseudomonas aeruginosa; nosocomial infection ... See more keywords
Protein Phosphatase-1 -targeted Small Molecules, Iron Chelators and Curcumin Analogs as HIV-1 Antivirals.
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DOI: 10.2174/1381612823666170704123620
Abstract: BACKGROUND Despite efficient suppression of HIV-1 replication, current antiviral drugs are not able to eradicate HIV-1 infection. Permanent HIV-1 suppression or complete eradication requires novel biological approaches and therapeutic strategies. Our previous studies showed that… read more here.
Keywords: curcumin analogs; phosphatase; small molecules; hiv transcription ... See more keywords
Attenuation of Scopolamine-Induced Amnesia via Cholinergic Modulation in Mice by Synthetic Curcumin Analogs
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DOI: 10.3390/molecules27082468
Abstract: Alzheimer’s disease is an emerging health disorder associated with cognitive decline and memory loss. In this study, six curcumin analogs (1a–1f) were synthesized and screened for in vitro cholinesterase inhibitory potential. On the basis of… read more here.
Keywords: curcumin analogs; attenuation scopolamine; induced amnesia; curcumin ... See more keywords
Curcumin and its Analogs and Carriers: Potential Therapeutic Strategies for Human Osteosarcoma
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DOI: 10.7150/ijbs.80590
Abstract: Curcumin is a natural polyphenol phytochemical derived from turmeric with antioxidant, anti-inflammatory, and anticancer properties but is concerned about poor solubility in water, absorption, and metabolic stability. Potent metastatic osteosarcoma is the most common primary… read more here.
Keywords: curcumin analogs; analogs carriers; carriers potential; human osteosarcoma ... See more keywords