Antiproliferative effect and autophagy induction of curcumin derivative ZYX02‐Na on the human lung cancer cells A549
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.22592
Abstract: At present, a large number of curcumin derivatives had been produced and identified aiming to replace the curcumin in view of its low bioavailability and stability. Here, a novel curcumin derivative ZYX02‐Na was first used… read more here.
Keywords: a549 cells; curcumin derivative; cells a549; derivative zyx02 ... See more keywords
Effects of FM0807, a novel curcumin derivative, on lipopolysaccharide-induced inflammatory factor release via the ROS/JNK/p53 pathway in RAW264.7 cells
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DOI: 10.1042/bsr20180849
Abstract: Purpose: Sepsis is a systemic inflammatory response caused by infection. Curcumin is known to have antioxidant and anti-inflammatory activities. FM0807, a curcumin derivative, was investigated in the present study to determine its effect on cytokines… read more here.
Keywords: ros jnk; raw 264; curcumin derivative; 264 cells ... See more keywords
A novel curcumin derivative CL-6 exerts antitumor effect in human gastric cancer cells by inducing apoptosis through Hippo–YAP signaling pathway
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DOI: 10.2147/ott.s196914
Abstract: Purpose Gastric carcinoma is the second most frequently diagnosed cancer and leading cause of cancer death in China. As a new generation of cancer therapeutic drug, CL-6, a curcumin derivative, shows better bioavailability than curcumin,… read more here.
Keywords: hippo yap; curcumin derivative; cancer; gastric cancer ... See more keywords
Redox-Responsive Lipidic Prodrug Nano-Delivery System Improves Antitumor Effect of Curcumin Derivative C210
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DOI: 10.3390/pharmaceutics15051546
Abstract: The poor bioavailability of curcumin and its derivatives limits their antitumor efficacy and clinical translation. Although curcumin derivative C210 has more potent antitumor activity than curcumin, it has a similar deficiency to curcumin. In order… read more here.
Keywords: curcumin derivative; nano delivery; redox responsive; prodrug ... See more keywords